| Literature DB >> 874769 |
S J Saxena, I L Honigberg, J T Stewart, J J Vallner.
Abstract
Dantrolene sodium can be determined in plasma and urine samples by high-pressure liquid chromatography without interference from its two major metabolites, the hydroxy and acetamido compounds. The minimum detectability of the drug using this procedure is 8 ng. The complete assay including extraction, evaporation, and separation steps can be performed in approximately 70 min with an accuracy of 1--3%.Entities:
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Year: 1977 PMID： 874769 DOI： 10.1002/jps.2600660543
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534