Literature DB >> 874612

The maytansinoids. Isolation, structural elucidation, and chemical interrelation of novel ansa macrolides.

S M Kupchan, Y Komoda, A R Branfman, A T Sneden, W A Court, G J Thomas, H P Hintz, R M Smith, A Karim, G A Howie, A K Verma, Y Nagao, R G Dailey, V A Zimmerly, W C Sumner.   

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Year:  1977        PMID： 874612     DOI： 10.1021/jo00434a001

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


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  13 in total

1.  Cyclization of synthetic seco-proansamitocins to ansamitocin macrolactams by Actinosynnema pretiosum as biocatalyst.

Authors:  Kirsten Harmrolfs; Marco Brünjes; Gerald Dräger; Heinz G Floss; Florenz Sasse; Florian Taft; Andreas Kirschning
Journal:  Chembiochem       Date:  2010-12-10       Impact factor: 3.164

2.  Selective isolation and ansamycin-targeted screenings of commensal actinomycetes from the "maytansinoids-producing" arboreal Trewia nudiflora.

Authors:  Na Zhu; Peiji Zhao; Yuemao Shen
Journal:  Curr Microbiol       Date:  2008-10-25       Impact factor: 2.188

Review 3.  Antibody-DM1 conjugates as cancer therapeutics.

Authors:  Manu Lopus
Journal:  Cancer Lett       Date:  2011-04-09       Impact factor: 8.679

4.  Structure-activity relationships among maytansinoids in their effect on the European corn borer,Ostrinia nubilalis (Hübner).

Authors:  R V Madrigal; B W Zilkowski; C R Smith
Journal:  J Chem Ecol       Date:  1985-04       Impact factor: 2.626

5.  Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability.

Authors:  Emin Oroudjev; Manu Lopus; Leslie Wilson; Charlene Audette; Carmela Provenzano; Hans Erickson; Yelena Kovtun; Ravi Chari; Mary Ann Jordan
Journal:  Mol Cancer Ther       Date:  2010-10       Impact factor: 6.261

6.  Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules.

Authors:  Manu Lopus; Emin Oroudjev; Leslie Wilson; Sharon Wilhelm; Wayne Widdison; Ravi Chari; Mary Ann Jordan
Journal:  Mol Cancer Ther       Date:  2010-10       Impact factor: 6.261

7.  Biosynthesis and accumulation of ergoline alkaloids in a mutualistic association between Ipomoea asarifolia (Convolvulaceae) and a clavicipitalean fungus.

Authors:  Anne Markert; Nicola Steffan; Kerstin Ploss; Sabine Hellwig; Ulrike Steiner; Christel Drewke; Shu-Ming Li; Wilhelm Boland; Eckhard Leistner
Journal:  Plant Physiol       Date:  2008-03-14       Impact factor: 8.340

8.  Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy.

Authors:  Colin T Huang; Xin Guo; Cyril Bařinka; Shawn E Lupold; Martin G Pomper; Kathleen Gabrielson; Venu Raman; Dmitri Artemov; Sudath Hapuarachchige
Journal:  Mol Pharm       Date:  2020-08-17       Impact factor: 4.939

9.  Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.

Authors:  Paola Marzullo; Zlata Boiarska; Helena Pérez-Peña; Anne-Catherine Abel; Beatriz Álvarez-Bernad; Daniel Lucena-Agell; Francesca Vasile; Maurizio Sironi; Karl-Heinz Altmann; Andrea E Prota; J Fernando Díaz; Stefano Pieraccini; Daniele Passarella
Journal:  Chemistry       Date:  2021-11-29       Impact factor: 5.020

10.  Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site.

Authors:  Jubina B Venghateri; Tilak Kumar Gupta; Paul J Verma; Ambarish Kunwar; Dulal Panda
Journal:  PLoS One       Date:  2013-10-04       Impact factor: 3.240
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