Literature DB >> 21077088

Cyclization of synthetic seco-proansamitocins to ansamitocin macrolactams by Actinosynnema pretiosum as biocatalyst.

Kirsten Harmrolfs1, Marco Brünjes, Gerald Dräger, Heinz G Floss, Florenz Sasse, Florian Taft, Andreas Kirschning.   

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Year:  2010        PMID: 21077088      PMCID: PMC3526346          DOI: 10.1002/cbic.201000422

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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  22 in total

1.  Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases.

Authors:  R M Kohli; J W Trauger; D Schwarzer; M A Marahiel; C T Walsh
Journal:  Biochemistry       Date:  2001-06-19       Impact factor: 3.162

2.  Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase.

Authors:  J W Trauger; R M Kohli; H D Mootz; M A Marahiel; C T Walsh
Journal:  Nature       Date:  2000-09-14       Impact factor: 49.962

3.  The thioesterase domain from a nonribosomal peptide synthetase as a cyclization catalyst for integrin binding peptides.

Authors:  Rahul M Kohli; Junichi Takagi; Christopher T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-22       Impact factor: 11.205

4.  Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase.

Authors:  J W Trauger; R M Kohli; C T Walsh
Journal:  Biochemistry       Date:  2001-06-19       Impact factor: 3.162

5.  Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus.

Authors:  S M Kupchan; Y Komoda; W A Court; G J Thomas; R M Smith; A Karim; C J Gilmore; R C Haltiwanger; R F Bryan
Journal:  J Am Chem Soc       Date:  1972-02-23       Impact factor: 15.419

6.  Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

Authors:  P R August; L Tang; Y J Yoon; S Ning; R Müller; T W Yu; M Taylor; D Hoffmann; C G Kim; X Zhang; C R Hutchinson; H G Floss
Journal:  Chem Biol       Date:  1998-02

7.  Timing of the Delta(10,12)-Delta(11,13) double bond migration during ansamitocin biosynthesis in Actinosynnema pretiosum.

Authors:  Florian Taft; Marco Brünjes; Tobias Knobloch; Heinz G Floss; Andreas Kirschning
Journal:  J Am Chem Soc       Date:  2009-03-25       Impact factor: 15.419

8.  Biosynthetic origin of aminobenzenoid nucleus (C7N-unit) of ansamitocin, a group of novel maytansinoid antibiotics.

Authors:  K Hatano; S Akiyama; M Asai; R W Rickards
Journal:  J Antibiot (Tokyo)       Date:  1982-10       Impact factor: 2.649

Review 9.  Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis.

Authors:  Florian Kopp; Mohamed A Marahiel
Journal:  Nat Prod Rep       Date:  2007-05-10       Impact factor: 13.423

Review 10.  Recent developments in the maytansinoid antitumor agents.

Authors:  John M Cassady; Kenneth K Chan; Heinz G Floss; Eckhard Leistner
Journal:  Chem Pharm Bull (Tokyo)       Date:  2004-01       Impact factor: 1.645

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  5 in total

1.  Broad substrate specificity of the amide synthase in S. hygroscopicus--new 20-membered macrolactones derived from geldanamycin.

Authors:  Simone Eichner; Timo Eichner; Heinz G Floss; Jörg Fohrer; Edgar Hofer; Florenz Sasse; Carsten Zeilinger; Andreas Kirschning
Journal:  J Am Chem Soc       Date:  2012-01-10       Impact factor: 15.419

2.  Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations.

Authors:  Tobias Knobloch; Gerald Dräger; Wera Collisi; Florenz Sasse; Andreas Kirschning
Journal:  Beilstein J Org Chem       Date:  2012-06-11       Impact factor: 2.883

3.  Preparation of new alkyne-modified ansamitocins by mutasynthesis.

Authors:  Kirsten Harmrolfs; Lena Mancuso; Binia Drung; Florenz Sasse; Andreas Kirschning
Journal:  Beilstein J Org Chem       Date:  2014-03-03       Impact factor: 2.883

Review 4.  Catalytic enantioselective synthesis of chiral organic compounds of ultra-high purity of >99% ee.

Authors:  Ei-ichi Negishi; Shiqing Xu
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2015       Impact factor: 3.493

5.  First Ring-Expanded Maytansin Lactone Accessed by a New Mutasynthetic Variant.

Authors:  Friederike Wesemann; Anja Heutling; Paul Wienecke; Andreas Kirschning
Journal:  Chembiochem       Date:  2020-07-02       Impact factor: 3.164

  5 in total

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