Literature DB >> 8740559

The sheath of the microfilaria of Brugia malayi from human infections has IgG on its surface.

R K Shenoy1, P G Rakesh, C I Baldwin, D A Denham.   

Abstract

Microfilariae (mf) of Brugia malayi from microfilaraemic people had human IgG on their sheath. Fluorescent antibody studies showed that the predominant IgG isotype was IgG3, with IgG4 and IgG1 being present in lower quantities. Human albumin could not be detected. The sera of patients with chronic disease contained high levels of an IgG2 antibody that reacted with the sheath of mf taken from other people.

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Year:  1996        PMID: 8740559     DOI: 10.1007/s004360050132

Source DB:  PubMed          Journal:  Parasitol Res        ISSN: 0932-0113            Impact factor:   2.289


  1 in total

1.  Anti-filarial immunity blocks parasite development and plays a protective role.

Authors:  Prakash Kumar Sahoo; Santosh K Panda; Ashok Kumar Satapathy; Sanghamitra Pati
Journal:  PLoS One       Date:  2018-06-21       Impact factor: 3.240

  1 in total

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