Literature DB >> 8738184

Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy. Part I. System development and control.

P A Hailey1, P Doherty, P Tapsell, T Oliver, P K Aldridge.   

Abstract

An automated system for the on-line monitoring of powder blending processes is described. The system employs near-infrared (NIR) spectroscopy using fibre-optics and a graphical user interface (GUI) developed in the LabVIEW environment. The complete supervisory control and data analysis (SCADA) software controls blender and spectrophotometer operation and performs statistical spectral data analysis in real time. A data analysis routine using standard deviation is described to demonstrate an approach to the real-time determination of blend homogeneity.

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Year:  1996        PMID: 8738184     DOI: 10.1016/0731-7085(95)01674-0

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  7 in total

1.  Next generation fluidized bed granulator automation.

Authors:  J Rantanen; M Känsäkoski; J Suhonen; J Tenhunen; S Lehtonen; T Rajalahti; J P Mannermaa; J Yliruusi
Journal:  AAPS PharmSciTech       Date:  2000-05-06       Impact factor: 3.246

2.  A novel method for analyzing thick tablets by near infrared spectroscopy.

Authors:  J L Ramirez; M K Bellamy; R J Romañac
Journal:  AAPS PharmSciTech       Date:  2001-07-12       Impact factor: 3.246

3.  Blend uniformity analysis using stream sampling and near infrared spectroscopy.

Authors:  Manuel Popo; Saly Romero-Torres; Carlos Conde; Rodolfo J Romañach
Journal:  AAPS PharmSciTech       Date:  2002       Impact factor: 3.246

4.  Near-infrared spectral imaging for quality assurance of pharmaceutical products: analysis of tablets to assess powder blend homogeneity.

Authors:  Robbe C Lyon; David S Lester; E Neil Lewis; Eunah Lee; Lawrence X Yu; Everett H Jefferson; Ajaz S Hussain
Journal:  AAPS PharmSciTech       Date:  2002       Impact factor: 3.246

5.  Quantitative analysis of film coating in a pan coater based on in-line sensor measurements.

Authors:  José D Pérez-Ramos; W Paul Findlay; Garnet Peck; Kenneth R Morris
Journal:  AAPS PharmSciTech       Date:  2005-09-20       Impact factor: 3.246

6.  The quantitative analysis of crystallinity using FT-Raman spectroscopy.

Authors:  L S Taylor; G Zografi
Journal:  Pharm Res       Date:  1998-05       Impact factor: 4.200

7.  NIR Spectroscopy as an Online PAT Tool for a Narrow Therapeutic Index Drug: Toward a Platform Approach Across Lab and Pilot Scales for Development of a Powder Blending Monitoring Method and Endpoint Determination.

Authors:  Sameer Talwar; Pallavi Pawar; Huiquan Wu; Koushik Sowrirajan; Suyang Wu; Benoît Igne; Richard Friedman; Fernando J Muzzio; James K Drennen
Journal:  AAPS J       Date:  2022-09-28       Impact factor: 3.603

  7 in total

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