| Literature DB >> 8730959 |
K C Olbrich1, T T Andersen, F A Blumenstock, R Bizios.
Abstract
Cell population motility and adhesion of rat skin fibroblasts were evaluated on aminophase glass modified with covalently-immobilized biologically active peptides, specifically, either arginine glycine-aspartic acid-serine (RGDS) or tyrosine-isoleucine-glycine-serine-arginine-glycine (YIGSRG). Fibroblast population motility was decreased and adhesion was increased on substrates modified with covalently immobilized RGDS peptide compared to substrates with the covalently immobilized non-adhesive peptides arginine-glycine-glutamic acid-serine and arginine-aspartic acid-glycine-serine. Fibroblast motility was not significantly changed on substrates modified with covalently-immobilized YIGSRG peptide; however, fibroblast adhesion was decreased on that substrate.Entities:
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Year: 1996 PMID: 8730959 DOI: 10.1016/0142-9612(96)81412-8
Source DB: PubMed Journal: Biomaterials ISSN: 0142-9612 Impact factor: 12.479