Literature DB >> 8720307

Free radical scavenging activity of curcuminoids.

N Sreejayan1, M N Rao.   

Abstract

Three natural curcuminoids (curcumin (CAS 458-37-7), demethoxycurcumin, bisdemethoxycurcumin) and acetylcurcumin were compared for their ability to scavenge superoxide radicals and to interact with 1,1-diphenyl-2-picryl-hydrazyl (DPPH) stable free radicals. The results showed that curcumin is the most potent scavenger of superoxide radicals followed by demethoxycurcumin and bisdemethoxycurcumin. Acetylcurcumin was inactive. Interaction with DPPH showed a similar activity profile. The study indicates that the phenolic group is essential for the free radical scavenging activity and presence of methoxy group further increases the activity.

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Year:  1996        PMID： 8720307

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN： 0004-4172


  63 in total

1.  Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.

Authors:  Miguel A Ortiz-Ortiz; José M Morán; Jose M Bravosanpedro; Rosa A González-Polo; Mireia Niso-Santano; Vellareddy Anantharam; Anumantha G Kanthasamy; Germán Soler; José M Fuentes
Journal:  Neurotoxicology       Date:  2009-08-04       Impact factor: 4.294

2.  Inhibition of oxidative stress and cytokine activity by curcumin in amelioration of endotoxin-induced experimental hepatoxicity in rodents.

Authors:  G Kaur; N Tirkey; S Bharrhan; V Chanana; P Rishi; K Chopra
Journal:  Clin Exp Immunol       Date:  2006-08       Impact factor: 4.330

3.  Antidiabetic andantioxidant properties, and α-amylase and α-glucosidase inhibition effects of triterpene saponins from Piper auritum.

Authors:  Rosa Martha Perez Gutierrez
Journal:  Food Sci Biotechnol       Date:  2016-02-29       Impact factor: 2.391

4.  Catalasic activity in fish liver: improvement of the UV to visible analytic method.

Authors:  Séverine Paris-Palacios; Laurence Delahaut; Alexis Carreras; Marielle Thomas; Sylvie Biagianti-Risbourg
Journal:  Fish Physiol Biochem       Date:  2012-12-07       Impact factor: 2.794

5.  Curcumin treatment protects rat retinal neurons against excitotoxicity: effect on N-methyl-D: -aspartate-induced intracellular Ca(2+) increase.

Authors:  A Matteucci; C Frank; M R Domenici; M Balduzzi; S Paradisi; G Carnovale-Scalzo; G Scorcia; F Malchiodi-Albedi
Journal:  Exp Brain Res       Date:  2005-08-03       Impact factor: 1.972

6.  Curcumin confers hepatoprotection against AFB1-induced toxicity via activating autophagy and ameliorating inflammation involving Nrf2/HO-1 signaling pathway.

Authors:  Ishfaq Muhammad; Xinghe Wang; Sihong Li; Rui Li; Xiuying Zhang
Journal:  Mol Biol Rep       Date:  2018-08-24       Impact factor: 2.316

7.  Curcumin decreased oxidative stress, inhibited NF-kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats.

Authors:  Suchittra Samuhasaneeto; Duangporn Thong-Ngam; Onanong Kulaputana; Doungsamon Suyasunanont; Naruemon Klaikeaw
Journal:  J Biomed Biotechnol       Date:  2009-07-06

8.  Antioxidant and cytotoxic activities of Centella asiatica (L) Urb.

Authors:  Frederico Pittella; Rafael C Dutra; Dalton D Junior; Miriam T P Lopes; Nádia R Barbosa
Journal:  Int J Mol Sci       Date:  2009-08-26       Impact factor: 6.208

9.  Free Radical Scavenging Activity of Leaves of Alocasia indica (Linn).

Authors:  W A Mulla; V R Salunkhe; S B Kuchekar; M N Qureshi
Journal:  Indian J Pharm Sci       Date:  2009-05       Impact factor: 0.975

10.  Quantification of phenolic constituents and antioxidant activity of Pterodon emarginatus vogel seeds.

Authors:  Rafael C Dutra; Magda N Leite; Nádia R Barbosa
Journal:  Int J Mol Sci       Date:  2008-04-18       Impact factor: 6.208
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