Literature DB >> 871426

Adenosine deaminase (ADA) activity in lymphocytes of normal individuals and patients with chronic lymphatic leukaemia.

B Ramot, F Brok-Simoni, N Barnea, I Bank, F Holtzmann.   

Abstract

Adenosine deaminase (adenosine aminophydrolase, ADA) activity was found to be low in lymphocytes of chronic lymphatic leukaemia (CLL) patients compared to normal lymphocytes. This was determined on 42 controls and 49 CLL patients. The mean activity in normal lymphocytes was found to be 4.35 +/- 3.34 mumol/h/10(8) cells while in CLL cells it was 2.45 +/- 2.54 mumol/h/10(8) cells.

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Year:  1977        PMID： 871426     DOI： 10.1111/j.1365-2141.1977.tb05756.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


  5 in total

1.  Uptake of free adenosine and adenosine from adenosine monophosphate by human peripheral blood lymphocytes: possible kinetic role for ecto-5'-nucleotidase in the regulation of intracellular adenosine.

Authors:  T Shah; R J Simpson; A D Webster; T J Peters
Journal:  Clin Exp Immunol       Date:  1986-10       Impact factor: 4.330

2.  Patterns of adenosine deaminase, ecto-5'-nucleotidase, poly(A)polymerase and surface light chain expression in chronic lymphocytic leukemias.

Authors:  T Trangas; N Courtis; A Gounaris; S Perez; D Kokkinopoulos; G A Pangalis; C M Tsiapalis
Journal:  Blut       Date:  1989-04

3.  Enzymes of the purine interconversion system in chronic lymphatic leukemia: decreased purine nucleoside phosphorylase and adenosine deaminase activity.

Authors:  H Ludwig; R Kuzmits; H Pietschmann; M M Müller
Journal:  Blut       Date:  1979-11

4.  Adenine and hypoxanthine metabolism in phythohemagglutinin-stimulated and unstimulated human lymphocytes.

Authors:  M M Müller; G Pischek; O Scheiner; H Stemberger; G Wiedermann
Journal:  Blut       Date:  1980-02

Review 5.  Enzyme and membrane markers in leukaemia: recent developments.

Authors:  A V Hoffbrand; G Janossy
Journal:  J Clin Pathol       Date:  1981-03       Impact factor: 3.411
  5 in total

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