Literature DB >> 871320

DNA swivel enzyme activity in a nuclear membrane fraction.

S Yoshida, G Ungers, B H Rosenberg.   

Abstract

DNA swivel (nicking-rejoining) enzyme activity has been studied in various cell fractions of a human lymphoid cell line. Swivel activity is found only in chromatin and in a nuclear membrane fraction containing DNA and possessing endogenous DNA synthesizing activity. Twenty percent of the total swivel activity and less than one percent of the total DNA are in the membrane fraction. The swivel enzyme is more tightly bound to the membrane fraction than to the chromatin fraction. These observations suggest that the swivel enzyme may be a replication factor, specifically bound to replicating DNA in the membrane fraction.

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Year:  1977        PMID: 871320      PMCID: PMC342421          DOI: 10.1093/nar/4.1.223

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  9 in total

1.  New DNA polymerase activity associated with nuclear membranes from a human lymphoid cell line.

Authors:  L F Cavalieri; E Carroll
Journal:  Biochem Biophys Res Commun       Date:  1975-12-15       Impact factor: 3.575

2.  Stepwise relaxation of supercoiled SV40 DNA.

Authors:  W Keller; I Wendel
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1975

3.  Characterization of purified DNA-relaxing enzyme from human tissue culture cells.

Authors:  W Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1975-07       Impact factor: 11.205

4.  Purification and demonstration of the enzymatic character of the nicking-closing protein from mouse L cells.

Authors:  H P Vosberg; J Vinograd
Journal:  Biochem Biophys Res Commun       Date:  1976-01-26       Impact factor: 3.575

5.  An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay).

Authors:  J J Champoux; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

6.  Interaction between DNA and an Escherichia coli protein omega.

Authors:  J C Wang
Journal:  J Mol Biol       Date:  1971-02-14       Impact factor: 5.469

7.  Isolation and partial characterisation of the relaxation protein from nuclei of cultured mouse and human cells.

Authors:  H P Vosberg; L I Grossman; J Vinograd
Journal:  Eur J Biochem       Date:  1975-06-16

8.  An omega protein from Drosophila melanogaster.

Authors:  W A Baase; J C Wang
Journal:  Biochemistry       Date:  1974-10-08       Impact factor: 3.162

9.  Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

Authors:  W Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

  9 in total
  2 in total

1.  Escherichia coli DNA topoisomerase I catalyzed linking of single-stranded rings of complementary base sequences.

Authors:  K Kirkegaard; J C Wang
Journal:  Nucleic Acids Res       Date:  1978-10       Impact factor: 16.971

2.  Initiation of DNA synthesis in the prematurely condensed chromosomes of G1 cells.

Authors:  S K Hanks; P N Rao
Journal:  J Cell Biol       Date:  1980-10       Impact factor: 10.539

  2 in total

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