| Literature DB >> 870966 |
M J Moses, L B Russel, N L Cacheiro.
Abstract
Pachytene chromosomes of mice heterozygous for known translocations are clearly depicted by configurations of the synaptonemal complexes in spread (whole mount) preparations. In one autosomal and two X-autosome translocations analyzed, breakpoints are identifiable; localization by measurement agrees with mitotic data and shows the translocations to be reciprocal. Synapsis with the Y is inhibited in one translocation in which the breakpoint is the pairing region of the X.Entities:
Mesh:
Year: 1977 PMID: 870966 DOI: 10.1126/science.870966
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728