Literature DB >> 8709270

Exogenous thymidine is preferentially incorporated into human cytomegalovirus DNA in infected human fibroblasts.

J Morin1, S Johann, B O'Hara, Y Gluzman.   

Abstract

The effect of human cytomegalovirus infection on cellular DNA synthesis in human fibroblasts was measured by fluorometry and by incorporation of radiolabeled thymidine. The results show that although HCMV infection stimulates cellular DNA synthesis in both quiescent and serum-stimulated cells, radiolabeled thymidine is almost exclusively incorporated into viral DNA.

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Year:  1996        PMID： 8709270      PMCID： PMC190668          DOI： 10.1128/JVI.70.9.6402-6404.1996

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  14 in total

1.  Induction of host DNA synthesis and DNA polymerase by DNA-negative temperature-sensitive mutants of human cytomegalovirus.

Authors:  K Yamanishi; F Rapp
Journal:  Virology       Date:  1979-04-15       Impact factor: 3.616

2.  The kinetics of serum-induced initiation of DNA synthesis in BHK 21/C13 cells, and the influence of exogenous adenosine.

Authors:  R F Brooks
Journal:  J Cell Physiol       Date:  1975-10       Impact factor: 6.384

Review 3.  Cell-activation responses to cytomegalovirus infection relationship to the phasing of CMV replication and to the induction of cellular damage.

Authors:  T Albrecht; I Boldogh; M Fons; C H Lee; S AbuBakar; J M Russell; W W Au
Journal:  Subcell Biochem       Date:  1989

4.  Carcinogenesis by avian sarcoma viruses. X. The decreased requirement for insulin-replaceable activity in serum for cell multiplication.

Authors:  H M Temin
Journal:  Int J Cancer       Date:  1968-11-15       Impact factor: 7.396

5.  A direct solubilization procedure for the determination of DNA and protein in cultured fibroblast monolayers.

Authors:  T Sorger; R J Germinario
Journal:  Anal Biochem       Date:  1983-05       Impact factor: 3.365

6.  Effect of UV-irradiated human cytomegalovirus infection on exogenous thymidine metabolism in human embryonic lung cells. Variation depending cells.

Authors:  S Ihara; S Saito; Y Watanabe
Journal:  Microbiol Immunol       Date:  1980       Impact factor: 1.955

7.  Thymidine-kinase in cytomegalovirus infected cells.

Authors:  V Závada; V Erban; D Rezácová; V Vonka
Journal:  Arch Virol       Date:  1976       Impact factor: 2.574

8.  Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest.

Authors:  F M Jault; J M Jault; F Ruchti; E A Fortunato; C Clark; J Corbeil; D D Richman; D H Spector
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

9.  Taxol inhibits stimulation of cell DNA synthesis by human cytomegalovirus.

Authors:  R L Ball; D H Carney; T Albrecht
Journal:  Exp Cell Res       Date:  1990-11       Impact factor: 3.905

10.  Human cytomegalovirus-induced inhibition of exogenous thymidine uptake into cell DNA in HEL cells stimulated to proliferate with serum.

Authors:  S Ihara; S Saito; Y Watanabe
Journal:  Tokai J Exp Clin Med       Date:  1980-07
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  4 in total

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Authors:  Steven Nagar; Linda Hanley-Bowdoin; Dominique Robertson
Journal:  Plant Cell       Date:  2002-12       Impact factor: 11.277

2.  The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells.

Authors:  E A Murphy; D N Streblow; J A Nelson; M F Stinski
Journal:  J Virol       Date:  2000-08       Impact factor: 5.103

3.  Human cytomegalovirus infection inhibits G1/S transition.

Authors:  D Dittmer; E S Mocarski
Journal:  J Virol       Date:  1997-02       Impact factor: 5.103

4.  The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirus.

Authors:  Emma Poole; Mark Bain; Linda Teague; Yoshinori Takei; Ron Laskey; John Sinclair
Journal:  PLoS One       Date:  2012-10-19       Impact factor: 3.240
  4 in total

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