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Literature DB >> 869922

The influence of lysosomes on glycogen metabolism.

Abstract

Lysosome-rich fractions were isolated from rat liver homogenates. In some fractions the lysosomes were separated from the contaminating mitchondria by the use of discontinuous Ficoll/sucrose gradients. Some glycogen was associated with lysosome fractions. This glycogen was of very large molecular size and of a quite different molecular-weight distribution from that isolated from the cytosol. It is suggested that appreciably more than 10% of cellular glycogen is located within the lysosome.

Entities: Chemical Species

Mesh：

Substances：
Liver Glycogen

Year: 1977 PMID： 869922 PMCID： PMC1164684 DOI： 10.1042/bj1630193

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

18 in total

1. MICRODETERMINATION OF MONOAMINE OXIDASE AND 5-HYDROXYTRYPTOPHAN DECARBOXYLASE ACTIVITIES IN NERVOUS TISSUES.

Authors: R E MCCAMAN; M W MCCAMAN; J M HUNT; M S SMITH
Journal: J Neurochem Date: 1965-01 Impact factor: 5.372

2. Tissue fractionation studies. 4. Comparative study of the binding of acid phosphatase, beta-glucuronidase and cathepsin by rat-liver particles.

Authors: R GIANETTO; C DE DUVE
Journal: Biochem J Date: 1955-03 Impact factor: 3.857

3. The sulphatase of ox liver. 7. The intracellular distribution of sulphatases A and B.

Authors: A B ROY
Journal: Biochem J Date: 1960-11 Impact factor: 3.857

4. A method for determining the sedimentation behavior of enzymes: application to protein mixtures.

Authors: R G MARTIN; B N AMES
Journal: J Biol Chem Date: 1961-05 Impact factor: 5.157

5. A method for the colorimetric estimation of glycogen with iodine.

Authors: C R KRISMAN
Journal: Anal Biochem Date: 1962-07 Impact factor: 3.365

6. Metabolic inhomogeneity of glycogen as a function of molecular weight.

Authors: H M KATZEN; D STETTEN; M R STETTEN
Journal: J Biol Chem Date: 1956-10 Impact factor: 5.157

7. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.

Authors: C DE DUVE; B C PRESSMAN; R GIANETTO; R WATTIAUX; F APPELMANS
Journal: Biochem J Date: 1955-08 Impact factor: 3.857

8. Post-mortem degradation of glycogen.

Authors: R Geddes; K B Rapson
Journal: FEBS Lett Date: 1973-05-01 Impact factor: 4.124

Review 9. The heterogeneity of lysosomes.

Authors: M Davies
Journal: Front Biol Date: 1975

10. Detection of hepatic maturation by Raman spectroscopy in mesenchymal stromal cells undergoing hepatic differentiation.

Authors: Hao-Hsiang Wu; Jennifer H Ho; Oscar K Lee
Journal: Stem Cell Res Ther Date: 2016-01-11 Impact factor: 6.832

The influence of lysosomes on glycogen metabolism.

1. MICRODETERMINATION OF MONOAMINE OXIDASE AND 5-HYDROXYTRYPTOPHAN DECARBOXYLASE ACTIVITIES IN NERVOUS TISSUES.

2. Tissue fractionation studies. 4. Comparative study of the binding of acid phosphatase, beta-glucuronidase and cathepsin by rat-liver particles.

3. The sulphatase of ox liver. 7. The intracellular distribution of sulphatases A and B.

4. A method for determining the sedimentation behavior of enzymes: application to protein mixtures.

5. A method for the colorimetric estimation of glycogen with iodine.

6. Metabolic inhomogeneity of glycogen as a function of molecular weight.

7. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.

8. Post-mortem degradation of glycogen.

Review 9. The heterogeneity of lysosomes.

10. A simple device for fractionating density gradients.

1. Acid maltase deficiency: a case study and review of the pathophysiological changes and proposed therapeutic measures.

2. Starch Binding Domain-containing Protein 1 Plays a Dominant Role in Glycogen Transport to Lysosomes in Liver.

3. The molecular size and shape of liver glycogen.

4. Lysosomal glycogen storage induced by Acarbose, a 1,4-alpha-glucosidase inhibitor.

Review 5. The respiratory neuromuscular system in Pompe disease.

6. Ultastructural localization of polysaccharides in the vacuolar system of an established cell line.

7. Comparative pathology of the canine model of glycogen storage disease type II (Pompe's disease).

8. Disturbance of lysosomal glycogen metabolism by liposomal anti-alpha-glucosidase and some anti-inflammatory drugs.

Review 9. Brain Glycogen Structure and Its Associated Proteins: Past, Present and Future.

10. Detection of hepatic maturation by Raman spectroscopy in mesenchymal stromal cells undergoing hepatic differentiation.