Literature DB >> 869918

Kinetic studies on the enzymes conjugating bile acids with taurine and glycine in bovine liver.

D A Vessey, M H Crissey, D Zakim.   

Abstract

Synthesis of glyco- or tauro-cholate from choloyl-CoA and the respective amino acid is shown to be catalysed by the soluble fraction of liver cells. Kinetic evidence supports the conclusion that there are separate enzymes for the synthesis of glycocholate and taurocholate. The kinetic parameters of these enzymes were determined.

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Year:  1977        PMID： 869918      PMCID： PMC1164677          DOI： 10.1042/bj1630181

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  6 in total

1.  Species differences in the conjugation of free bile acids with taurine and glycine.

Authors:  J BREMER
Journal:  Biochem J       Date:  1956-07       Impact factor: 3.857

2.  The enzymic synthesis of taurocholic acid: a qualitative study.

Authors:  W H ELLIOTT
Journal:  Biochem J       Date:  1956-03       Impact factor: 3.857

3.  Enzymic activation of cholic acid involving coenzyme A.

Authors:  W H ELLIOTT
Journal:  Biochim Biophys Acta       Date:  1955-07

4.  Enzymatic synthesis of cholyl coA and taurocholic acid.

Authors:  M D SIPERSTEIN; A W MURRAY
Journal:  Science       Date:  1956-03-02       Impact factor: 47.728

5.  Synthesis of coenzyme A esters of some bile acids.

Authors:  P P Shah; E Staple
Journal:  Steroids       Date:  1968-11       Impact factor: 2.668

6.  The synthesis of taurocholic and glycocholic acids by preparations of human liver. I. Distribution of activity between subcellular fractions.

Authors:  T Scherstén
Journal:  Biochim Biophys Acta       Date:  1967-06-13
  6 in total
  5 in total

Review 1.  FXR signaling in the enterohepatic system.

Authors:  Tsutomu Matsubara; Fei Li; Frank J Gonzalez
Journal:  Mol Cell Endocrinol       Date:  2012-05-17       Impact factor: 4.102

2.  Subcellular distribution of hepatic bile acid-conjugating enzymes.

Authors:  W C Lim; T W Jordan
Journal:  Biochem J       Date:  1981-09-01       Impact factor: 3.857

3.  The biochemical basis for the conjugation of bile acids with either glycine or taurine.

Authors:  D A Vessey
Journal:  Biochem J       Date:  1978-08-15       Impact factor: 3.857

4.  Primary culture of rat hepatocytes entrapped in cylindrical collagen gels: an in vitro system with application to the bioartificial liver. Rat hepatocytes cultured in cylindrical collagen gels.

Authors:  S L Nyberg; R A Shatford; W D Payne; W S Hu; F B Cerra
Journal:  Cytotechnology       Date:  1992       Impact factor: 2.058

Review 5.  Deciphering the nuclear bile acid receptor FXR paradigm.

Authors:  Salvatore Modica; Raffaella M Gadaleta; Antonio Moschetta
Journal:  Nucl Recept Signal       Date:  2010-11-19
  5 in total

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