| Literature DB >> 8699077 |
J H Kao1, P J Chen, S C Hsiang, W Chen, D S Chen.
Abstract
A group of flavi-like GB viruses (GBV-A, -B, and -C) has been discovered and partially characterized. Only GBV-C is found in humans. Nucleotide sequences of the putative helicase gene of the GBV-C genome were determined in 21 Taiwanese patients and compared with isolates from Africa and North America by phylogenetic analysis. The average similarities of Taiwanese isolates to those from West Africa, East Africa, Canada, and United States were 83%, 85%, 78%, and 82%, respectively. Phylogenetic analysis of the NS3 region showed that 81% of the Taiwanese isolates were more closely related to the East African isolate. GBV-C isolates from Taiwan could be classified into at least 3 groups. These data suggest that GBV-C isolates cloned from different geographic areas have genetic heterogeneity.Entities:
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Year: 1996 PMID： 8699077 DOI： 10.1093/infdis/174.2.410
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226