Literature DB >> 8698636

Novel triterpene sulfates from Fusarium compactum using a rhinovirus 3C protease inhibitor screen.

G M Brill1, W M Kati, D Montgomery, J P Karwowski, P E Humphrey, M Jackson, J J Clement, S Kadam, R H Chen, J B McAlpine.   

Abstract

Two novel triterpene sulfates have been isolated from Fusarium compactum by bioactivity-directed fractionation using an assay which measures the inhibition of proteolytic activity of rhinovirus 3C protease on a fluorogenic peptide substrate. The compounds were purified by countercurrent and reverse phase chromatographies. NMR, MS, UV and IR studies revealed two triterpene sulfates, uncommon metabolites of terrestrial fungi.

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Year:  1996        PMID: 8698636     DOI: 10.7164/antibiotics.49.541

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Molecular modelling and simulation techniques to investigate the effects of fungal metabolites on the SARS-CoV-2 RdRp protein inhibition.

Authors:  Uday M Muddapur; Shrikanth Badiger; Ibrahim Ahmed Shaikh; Mohammed M Ghoneim; Saleh A Alshamrani; Mater H Mahnashi; Fahad Alsaikhan; Mohamed El-Sherbiny; Rasha Hamed Al-Serwi; Aejaz Abdul Latif Khan; Basheerahmed Abdulaziz Mannasaheb; Amal Bahafi; S M Shakeel Iqubal; Touseef Begum; Helen Suban Mohammed Gouse; Tasneem Mohammed; Veeranna S Hombalimath
Journal:  J King Saud Univ Sci       Date:  2022-06-03

2.  New Enzyme-Inhibitory Triterpenoid from Marine Macro Brown Alga Padina boergesenii Allender & Kraft.

Authors:  Liaqat Ali; Abdul Latif Khan; Muhammad Al-Broumi; Rashid Al-Harrasi; Lubna Al-Kharusi; Javid Hussain; Ahmed Al-Harrasi
Journal:  Mar Drugs       Date:  2017-01-18       Impact factor: 5.118

  2 in total

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