| Literature DB >> 8698092 |
H Haraguchi1, H Ishikawa, S Sakai, B P Ying, I Kubo.
Abstract
A diterpenoid, totarol (1), from Podocarpus nagi was evaluated as an antioxidant. This diterpenoid inhibited autoxidation of linoleic acid. Mitochondrial and microsomal lipid peroxidation induced by Fe(III)-ADP/NADH or Fe(III)-ADP/NADPH were also inhibited. Nagilactone E (2), a norditerpene lactone isolated from the same source, had no antioxidative activity. Furthermore, totarol protected red cells against oxidative hemolysis. This diterpene was shown to be effective in protecting biological systems against oxidative stresses.Entities:
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Year: 1996 PMID： 8698092 DOI： 10.1007/bf01969731
Source DB: PubMed Journal: Experientia ISSN： 0014-4754