BACKGROUND: After the first successful laparoscopic closure of a perforated peptic ulcer in 1990, 18 patients withlaparoscopic closure were compared to 16 patients with conventional surgery. METHODS: The endpoint adverse events (complications), pain intensity, operation time, fever, leucocytosis, and duration of hospital stay showed no clinically relevant differences. RESULTS:Consumption of analgesics was lower in the laparoscopic group. CONCLUSIONS:Laparoscopic closureof perforated peptic ulcer is technically feasible. The safety of the method and the benefit for the patient need proof by means of a randomized controlled trial.
RCT Entities:
BACKGROUND: After the first successful laparoscopic closure of a perforated peptic ulcer in 1990, 18 patients with laparoscopic closure were compared to 16 patients with conventional surgery. METHODS: The endpoint adverse events (complications), pain intensity, operation time, fever, leucocytosis, and duration of hospital stay showed no clinically relevant differences. RESULTS: Consumption of analgesics was lower in the laparoscopic group. CONCLUSIONS: Laparoscopic closure of perforated peptic ulcer is technically feasible. The safety of the method and the benefit for the patient need proof by means of a randomized controlled trial.
Authors: Wing T Siu; Heng T Leong; Bonita K B Law; Chun H Chau; Anthony C N Li; Kai H Fung; Yuk P Tai; Michael K W Li Journal: Ann Surg Date: 2002-03 Impact factor: 12.969
Authors: Markus K Muller; Simon Wrann; Jeannette Widmer; Jennifer Klasen; Markus Weber; Dieter Hahnloser Journal: World J Surg Date: 2016-09 Impact factor: 3.352