Literature DB >> 8694606

Reduced mortality and morbidity for ascending aortic aneurysm resection regardless of cause.

L H Cohn1, R J Rizzo, D H Adams, S F Aranki, G S Couper, N Beckel, J J Collins.   

Abstract

BACKGROUND: This study was done to answer the question, "What is the current risk of resection of ascending aortic aneurysms regardless of acuity or cause?"
METHODS: One hundred fifteen consecutive patients who underwent ascending aortic aneurysm repair from January 1, 1990, to July 1, 1995, were retrospectively reviewed, excluding those with acute ascending aortic dissection. The mean age was 59 years; 55% were male. Concomitant procedures included coronary artery bypass in 23 (20%) and arch repair in 12 (10%). In group 1, 54 patients had replacement of the aortic valve, root, and ascending aorta with a valve-graft conduit using the "Bentall" technique, and of these 19 (35%) had Marfan's syndrome. In group II, 44 patients had separate aortic valve repair or replacement and supracoronary ascending aortic replacement. In group III, 17 patients had supracoronary ascending aortic replacement, without aortic valve operation. Operative techniques included frequent use of (1) intraoperative transesophageal echocardiography or epiaortic ultrasound scanning of the ascending and descending thoracic aorta to help guide arterial cannulation, avoid atherosclerotic embolization, and assess the repair; (2) antegrade and retrograde multidose cold blood cardioplegia for myocardial protection; (3) exclusion and button anastomotic techniques to ensure secure suture lines; (4) antifibrinolytic agents and collagen-impregnated aortic grafts to reduce bleeding; and (5) deep hypothermic circulatory arrest and the open distal anastomotic technique in patients with distal ascending and arch aortic disease.
RESULTS: Operative mortality overall was 2/115 (1.7%). Mortality was 1/54 (1.8) in group I and 1/44 (2%) in group II, and there was no mortality in group III. The overall postoperative morbidity was 3% due to bleeding, 2% due to stroke, and 1% due to myocardial infarction. The length of stay in the past year has decreased to less than 7 days.
CONCLUSIONS: The current risk for ascending aortic aneurysm repair is low (< 2%) whether or not the aortic root or valve also needs repair, regardless of the cause of the aneurysm.

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Year:  1996        PMID: 8694606

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  11 in total

1.  Combined grafting of thoracic aortic aneurysm and cardiac repair using continuous cold-blood coronary perfusion.

Authors:  Y Takahara; Y Sudou; H Nakano; Y Niizuma; T Sato; H Ishikawa; N Nakajima
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2001-02

2.  Concomitant replacement of the aortic root and aortic arch with or without secondary thoracoabdominal aorta replacement.

Authors:  K Tabayashi; H Yokoyama; A Iguchi; S Watanabe; T Fukujyu; Y Tsuru; K Niibori; H Akimoto; M Tofukuji
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2001-01

3.  Risk factors for prophylactic proximal aortic replacement in the current era.

Authors:  Takashi Kunihara; Diana Aicher; Mitsuru Asano; Hiroaki Takahashi; Dierk Heimann; Fumihiro Sata; Hans-Joachim Schäfers
Journal:  Clin Res Cardiol       Date:  2014-01-24       Impact factor: 5.460

4.  Hypothermic circulatory arrest does not increase the risk of ascending thoracic aortic aneurysm resection.

Authors:  R C King; I L Kron; R C Kanithanon; K S Shockey; W D Spotnitz; C G Tribble
Journal:  Ann Surg       Date:  1998-05       Impact factor: 12.969

5.  Emergency surgery results in life-threatening thoracic aortic disease.

Authors:  Yoshito Kawachi; Yoshihiro Toshima; Atsuhiro Nakashima; Kouichi Arinaga; Isao Komesu
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2002-04

6.  The use of a stentless porcine bioprosthesis to repair an ascending aortic aneurysm in combination with aortic valve regurgitation.

Authors:  B Akpinar; I Sanisoğlu; C Konuralp; H Akay; M Güden; B Sönmez
Journal:  Tex Heart Inst J       Date:  1999

7.  Long term outcomes of aortic root replacement: 18 years' experience.

Authors:  Ji Hyun Bang; Yu-Mi Im; Joon Bum Kim; Suk Jung Choo; Cheol Hyun Chung; Jae Won Lee; Sung-Ho Jung
Journal:  Korean J Thorac Cardiovasc Surg       Date:  2013-04-09

8.  Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm.

Authors:  Emanuela Branchetti; Paolo Poggio; Rachana Sainger; Eric Shang; Juan B Grau; Benjamin M Jackson; Eric K Lai; Michael S Parmacek; Robert C Gorman; Joseph H Gorman; Joseph E Bavaria; Giovanni Ferrari
Journal:  Cardiovasc Res       Date:  2013-08-28       Impact factor: 10.787

9.  Quality of life after replacement of the ascending aorta in patients with true aneurysms.

Authors:  Folke Lohse; Nora Lang; Wolfgang Schiller; Wilhelm Roell; Oliver Dewald; Claus-Juergen Preusse; Armin Welz; Christoph Schmitz
Journal:  Tex Heart Inst J       Date:  2009

10.  Contemporary results for proximal aortic replacement in North America.

Authors:  Judson B Williams; Eric D Peterson; Yue Zhao; Sean M O'Brien; Nicholas D Andersen; D Craig Miller; Edward P Chen; G Chad Hughes
Journal:  J Am Coll Cardiol       Date:  2012-09-05       Impact factor: 24.094

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