Literature DB >> 8692707

High efficiency, long-term clinical expression of cottontail rabbit papillomavirus (CRPV) DNA in rabbit skin following particle-mediated DNA transfer.

W Xiao1, J L Brandsma.   

Abstract

The ability of skin to support long lasting expression of genes delivered with a particle-mediated system was evaluated in rabbits inoculated with cottontail rabbit papillomavirus (CRPV) DNA. The optimal delivery force for maximal gene expression in rabbit skin was determined in transient beta-galactosidase assays. Forty-five sites in four rabbits were then inoculated at 350-400 p.s.i. with CRPV DNA. All sites (100%) formed papillomas with multiple papillomas at most sites. These results support the feasibility of using a particle-mediated delivery system for gene therapy and suggest that some papillomavirus features, such an origin of replication, may be well suited for use in vectors to target long term expression to skin.

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Year:  1996        PMID： 8692707      PMCID： PMC145979          DOI： 10.1093/nar/24.13.2620

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  13 in total

1.  Use of a rapid, efficient inoculation method to induce papillomas by cottontail rabbit papillomavirus DNA shows that the E7 gene is required.

Authors:  J L Brandsma; Z H Yang; S W Barthold; E A Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-01       Impact factor: 11.205

Review 2.  The papillomavirus E2 regulatory proteins.

Authors:  A A McBride; H Romanczuk; P M Howley
Journal:  J Biol Chem       Date:  1991-10-05       Impact factor: 5.157

Review 3.  Animal models of human-papillomavirus-associated oncogenesis.

Authors:  J L Brandsma
Journal:  Intervirology       Date:  1994       Impact factor: 1.763

4.  Gene therapy's growing pains.

Authors:  E Marshall
Journal:  Science       Date:  1995-08-25       Impact factor: 47.728

Review 5.  Epidermis: an attractive target tissue for gene therapy.

Authors:  D A Greenhalgh; J A Rothnagel; D R Roop
Journal:  J Invest Dermatol       Date:  1994-11       Impact factor: 8.551

6.  Papilloma formation by cottontail rabbit papillomavirus requires E1 and E2 regulatory genes in addition to E6 and E7 transforming genes.

Authors:  X Wu; W Xiao; J L Brandsma
Journal:  J Virol       Date:  1994-09       Impact factor: 5.103

7.  The putative E5 open reading frame of cottontail rabbit papillomavirus is dispensable for papilloma formation in domestic rabbits.

Authors:  J L Brandsma; Z H Yang; D DiMaio; S W Barthold; E Johnson; W Xiao
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

Review 8.  Gene transfer into mammalian somatic cells in vivo.

Authors:  N S Yang
Journal:  Crit Rev Biotechnol       Date:  1992       Impact factor: 8.429

9.  Identification of three transforming proteins encoded by cottontail rabbit papillomavirus.

Authors:  C Meyers; J Harry; Y L Lin; F O Wettstein
Journal:  J Virol       Date:  1992-03       Impact factor: 5.103

10.  Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector.

Authors:  N Sarver; P Gruss; M F Law; G Khoury; P M Howley
Journal:  Mol Cell Biol       Date:  1981-06       Impact factor: 4.272
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  11 in total

1.  A novel recombinant papillomavirus genome enabling in vivo RNA interference reveals that YB-1, which interacts with the viral regulatory protein E2, is required for CRPV-induced tumor formation in vivo.

Authors:  Natalie Leiprecht; Ekaterina Notz; Johanna Schuetz; Juliane Haedicke; Frank Stubenrauch; Thomas Iftner
Journal:  Am J Cancer Res       Date:  2014-05-26       Impact factor: 6.166

2.  Orf Virus-Based Therapeutic Vaccine for Treatment of Papillomavirus-Induced Tumors.

Authors:  M Schneider; M Müller; A Yigitliler; J Xi; C Simon; T Feger; H-J Rziha; F Stubenrauch; H-G Rammensee; T Iftner; R Amann
Journal:  J Virol       Date:  2020-07-16       Impact factor: 5.103

3.  A transactivator function of cottontail rabbit papillomavirus e2 is essential for tumor induction in rabbits.

Authors:  Sonja Jeckel; Evamaria Huber; Frank Stubenrauch; Thomas Iftner
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

4.  Variation in the nucleotide sequence of cottontail rabbit papillomavirus a and b subtypes affects wart regression and malignant transformation and level of viral replication in domestic rabbits.

Authors:  J Salmon; M Nonnenmacher; S Cazé; P Flamant; O Croissant; G Orth; F Breitburd
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

5.  Impact of genetic changes to the CRPV genome and their application to the study of pathogenesis in vivo.

Authors:  Jiafen Hu; Nancy M Cladel; Karla Balogh; Lynn Budgeon; Neil D Christensen
Journal:  Virology       Date:  2006-10-04       Impact factor: 3.616

Review 6.  The rabbit papillomavirus model: a valuable tool to study viral-host interactions.

Authors:  Nancy M Cladel; Xuwen Peng; Neil Christensen; Jiafen Hu
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2019-05-27       Impact factor: 6.237

7.  Identification of the E9/E2C cDNA and functional characterization of the gene product reveal a new repressor of transcription and replication in cottontail rabbit papillomavirus.

Authors:  Sonja Jeckel; Ekaterina Loetzsch; Evamaria Huber; Frank Stubenrauch; Thomas Iftner
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103

8.  Intracutaneous DNA vaccination with the E8 gene of cottontail rabbit papillomavirus induces protective immunity against virus challenge in rabbits.

Authors:  Jiafen Hu; Ricai Han; Nancy M Cladel; Martin D Pickel; Neil D Christensen
Journal:  J Virol       Date:  2002-07       Impact factor: 5.103

9.  Low-volume jet injection for intradermal immunization in rabbits.

Authors:  Shuxun Ren; Minglin Li; Joanne M Smith; Louis J DeTolla; Priscilla A Furth
Journal:  BMC Biotechnol       Date:  2002-05-23       Impact factor: 2.563

10.  The viral E4 protein is required for the completion of the cottontail rabbit papillomavirus productive cycle in vivo.

Authors:  Woei L Peh; Janet L Brandsma; Neil D Christensen; Nancy M Cladel; Xing Wu; John Doorbar
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103
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