Literature DB >> 8688087

Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.

C J Bult1, O White, G J Olsen, L Zhou, R D Fleischmann, G G Sutton, J A Blake, L M FitzGerald, R A Clayton, J D Gocayne, A R Kerlavage, B A Dougherty, J F Tomb, M D Adams, C I Reich, R Overbeek, E F Kirkness, K G Weinstock, J M Merrick, A Glodek, J L Scott, N S Geoghagen, J C Venter.   

Abstract

The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome random sequencing. A total of 1738 predicted protein-coding genes were identified; however, only a minority of these (38 percent) could be assigned a putative cellular role with high confidence. Although the majority of genes related to energy production, cell division, and metabolism in M. jannaschii are most similar to those found in Bacteria, most of the genes involved in transcription, translation, and replication in M. jannaschii are more similar to those found in Eukaryotes.

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Year:  1996        PMID: 8688087     DOI: 10.1126/science.273.5278.1058

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


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