Literature DB >> 8678197

Timeliness and use of antibiotic prophylaxis in selected inpatient surgical procedures. The Antibiotic Prophylaxis Study Group.

A Silver1, A Eichorn, J Kral, G Pickett, P Barie, V Pryor, M B Dearie.   

Abstract

BACKGROUND: Twenty-five percent of all nosocomial infections are wound infections. Professional guidelines support the timely use of preoperative prophylaxis for prevention of postoperative wound infections. Barriers exist in implementing this practice. IPRO, the New York State peer review organization, as part of the Health Care Financing Administration's Health Care Quality Improvement Program, sought to determine the proportion of patients receiving timely antibiotic prophylaxis for aortic grafts, hip replacements and colon resections in 44 hospitals in New York State.
METHODS: IPRO conducted a retrospective medical record review of 44 hospitals through out New York State stratified for teaching, nonteaching status. A sample was drawn of 2651 patients, 2256 from Medicare and 395 from Medicaid, undergoing either abdominal aortic aneurysm repair, partial or total hip replacement or large bowel resection. The study determined the proportion of patients who had documentation of receiving antibiotics and those who received antibiotics timely, that is less than or equal to 2 hours preoperatively.
RESULTS: Eighty-six percent of patients had documentation of receiving an antibiotic. Forty-six percent of aneurysm repairs and 60% of hip replacements had evidence of receiving timely antibiotic prophylaxis, that is within 2 hours prior to surgery. For colon resections, 73% of cases had either oral prophylaxis or timely parenteral therapy. An increased proportion of patients had received parenteral antibiotics prematurely as the surgical start time occurred later in the day. A total of 44 different antibiotics were recorded for prophylaxis.
CONCLUSIONS: Antibiotic prophylaxis was performed in 81% to 94% of cases, however, anywhere from 27% to 54% of all cases did not receive antibiotics in a timely fashion. By delegating implementation of ordered antibiotic prophylaxis to the anesthesia team, timing may be improved and the incidence of postoperative wound infections may decrease.

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Year:  1996        PMID: 8678197     DOI: 10.1016/s0002-9610(96)00036-0

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  13 in total

Review 1.  Preventing postoperative infections: current treatment recommendations.

Authors:  I C Gyssens
Journal:  Drugs       Date:  1999-02       Impact factor: 9.546

2.  Adherence to guidelines for antibiotic prophylaxis in surgery patients in German hospitals: a multicentre evaluation involving pharmacy interns.

Authors:  C Hohmann; C Eickhoff; R Radziwill; M Schulz
Journal:  Infection       Date:  2011-10-15       Impact factor: 3.553

3.  Exploring obstacles to proper timing of prophylactic antibiotics for surgical site infections.

Authors:  J A Tan; V N Naik; L Lingard
Journal:  Qual Saf Health Care       Date:  2006-02

Review 4.  Factors influencing antibiotic prophylaxis for surgical site infection prevention in general surgery: a review of the literature.

Authors:  Anna R Gagliardi; Darlene Fenech; Cagla Eskicioglu; Avery B Nathens; Robin McLeod
Journal:  Can J Surg       Date:  2009-12       Impact factor: 2.089

5.  Survey of surgical antimicrobial prophylaxis in czech republic.

Authors:  Retnosari Andrajati; Jiri Vlcek; Milan Kolar; Ráchel Pípalová
Journal:  Pharm World Sci       Date:  2005-12

6.  Surgical antibiotic prophylaxis: effect in postoperative infections.

Authors:  A H Fernández; V Monge; M A Garcinuño
Journal:  Eur J Epidemiol       Date:  2001       Impact factor: 8.082

7.  Is there an improvement of antibiotic use in China? Evidence from the usage analysis of combination antibiotic therapy for type I incisions in 244 hospitals.

Authors:  Wen-Juan Zhou; Zhen-Ni Luo; Chang-Min Tang; Xiao-Xu Zou; Lu Zhao; Peng-Qian Fang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2016-10-18

8.  The SURgical PAtient Safety System (SURPASS) checklist optimizes timing of antibiotic prophylaxis.

Authors:  Eefje N de Vries; Lucia Dijkstra; Susanne M Smorenburg; R Peter Meijer; Marja A Boermeester
Journal:  Patient Saf Surg       Date:  2010-04-13

9.  Risk of surgical site infection and efficacy of antibiotic prophylaxis: a cohort study of appendectomy patients in Thailand.

Authors:  Nongyao Kasatpibal; Mette Nørgaard; Henrik Toft Sørensen; Henrik Carl Schønheyder; Silom Jamulitrat; Virasakdi Chongsuvivatwong
Journal:  BMC Infect Dis       Date:  2006-07-12       Impact factor: 3.090

10.  Timing of surgical antibiotic prophylaxis administration: complexities of analysis.

Authors:  Carrie Cartmill; Lorelei Lingard; Glenn Regehr; Sherry Espin; John Bohnen; Ross Baker; Lorne Rotstein
Journal:  BMC Med Res Methodol       Date:  2009-06-23       Impact factor: 4.615

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