Literature DB >> 8676522

Sequence determinants of 3A-mediated resistance to enviroxime in rhinoviruses and enteroviruses.

B A Heinz1, L M Vance.   

Abstract

Using site-directed mutagenesis of the 3A coding region of rhinovirus 14, we have expanded our analysis of resistance to enviroxime. We have observed that high and low levels of drug resistance involve two domains within 3A and that the amino acid at position 30 is critical in determining resistance.

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Year:  1996        PMID： 8676522      PMCID： PMC190432     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  cis-acting lesions targeted to the hydrophobic domain of a poliovirus membrane protein involved in RNA replication.

Authors:  C Giachetti; S S Hwang; B L Semler
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

2.  Role of a viral membrane polypeptide in strand-specific initiation of poliovirus RNA synthesis.

Authors:  C Giachetti; B L Semler
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

3.  Association of polioviral proteins of the P2 genomic region with the viral replication complex and virus-induced membrane synthesis as visualized by electron microscopic immunocytochemistry and autoradiography.

Authors:  K Bienz; D Egger; L Pasamontes
Journal:  Virology       Date:  1987-09       Impact factor: 3.616

4.  Initiation of poliovirus plus-strand RNA synthesis in a membrane complex of infected HeLa cells.

Authors:  N Takeda; R J Kuhn; C F Yang; T Takegami; E Wimmer
Journal:  J Virol       Date:  1986-10       Impact factor: 5.103

5.  High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis.

Authors:  B C Cunningham; J A Wells
Journal:  Science       Date:  1989-06-02       Impact factor: 47.728

6.  The role of cytoplasmic membranes in poliovirus biosynthesis.

Authors:  L A Caliguiri; I Tamm
Journal:  Virology       Date:  1970-09       Impact factor: 3.616

7.  Studies with poliovirus polymerase 3Dpol. Stimulation of poly(U) synthesis in vitro by purified poliovirus protein 3AB.

Authors:  A V Paul; X Cao; K S Harris; J Lama; E Wimmer
Journal:  J Biol Chem       Date:  1994-11-18       Impact factor: 5.157

8.  Membrane-dependent uridylylation of the genome-linked protein VPg of poliovirus.

Authors:  T Takegami; R J Kuhn; C W Anderson; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1983-12       Impact factor: 11.205

9.  ATP is required for initiation of poliovirus RNA synthesis in vitro: demonstration of tyrosine-phosphate linkage between in vitro-synthesized RNA and genome-linked protein.

Authors:  C D Morrow; J Hocko; M Navab; A Dasgupta
Journal:  J Virol       Date:  1984-05       Impact factor: 5.103

10.  Systematic mutational analysis of the yeast ACT1 gene.

Authors:  K F Wertman; D G Drubin; D Botstein
Journal:  Genetics       Date:  1992-10       Impact factor: 4.562
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  21 in total

1.  Enterovirus D68 Antivirals: Past, Present, and Future.

Authors:  Yanmei Hu; Rami Musharrafieh; Madeleine Zheng; Jun Wang
Journal:  ACS Infect Dis       Date:  2020-05-14       Impact factor: 5.084

2.  Poliovirus 2C region functions during encapsidation of viral RNA.

Authors:  L M Vance; N Moscufo; M Chow; B A Heinz
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

3.  Characterization of protein-protein interactions critical for poliovirus replication: analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase.

Authors:  Daniel M Strauss; Deborah S Wuttke
Journal:  J Virol       Date:  2007-04-04       Impact factor: 5.103

4.  Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.

Authors:  Armando M De Palma; Hendrik Jan Thibaut; Lonneke van der Linden; Kjerstin Lanke; Ward Heggermont; Stephen Ireland; Robert Andrews; Murty Arimilli; Taleb H Al-Tel; Erik De Clercq; Frank van Kuppeveld; Johan Neyts
Journal:  Antimicrob Agents Chemother       Date:  2009-02-23       Impact factor: 5.191

5.  Phosphatidylinositol 4-kinase III beta is essential for replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo.

Authors:  Catherine Spickler; Julie Lippens; Marie-Kristine Laberge; Sophie Desmeules; Édith Bellavance; Michel Garneau; Tim Guo; Oliver Hucke; Pieter Leyssen; Johan Neyts; Fréderic H Vaillancourt; Anne Décor; Jeff O'Meara; Michael Franti; Annick Gauthier
Journal:  Antimicrob Agents Chemother       Date:  2013-05-06       Impact factor: 5.191

Review 6.  Molecular typing of enteroviruses: current status and future requirements. The European Union Concerted Action on Virus Meningitis and Encephalitis.

Authors:  P Muir; U Kämmerer; K Korn; M N Mulders; T Pöyry; B Weissbrich; R Kandolf; G M Cleator; A M van Loon
Journal:  Clin Microbiol Rev       Date:  1998-01       Impact factor: 26.132

7.  Emergence in Asia of foot-and-mouth disease viruses with altered host range: characterization of alterations in the 3A protein.

Authors:  N J Knowles; P R Davies; T Henry; V O'Donnell; J M Pacheco; P W Mason
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

8.  Mutations in the 2C region of poliovirus responsible for altered sensitivity to benzimidazole derivatives.

Authors:  H Shimizu; M Agoh; Y Agoh; H Yoshida; K Yoshii; T Yoneyama; A Hagiwara; T Miyamura
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

9.  New small-molecule inhibitors effectively blocking picornavirus replication.

Authors:  Lauren A Ford Siltz; Ekaterina G Viktorova; Ben Zhang; Diana Kouiavskaia; Eugenia Dragunsky; Konstantin Chumakov; Lyle Isaacs; George A Belov
Journal:  J Virol       Date:  2014-07-09       Impact factor: 5.103

10.  Membrane topography of the hydrophobic anchor sequence of poliovirus 3A and 3AB proteins and the functional effect of 3A/3AB membrane association upon RNA replication.

Authors:  Kentaro Fujita; Shyam S Krishnakumar; David Franco; Aniko V Paul; Erwin London; Eckard Wimmer
Journal:  Biochemistry       Date:  2007-04-07       Impact factor: 3.162
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