Literature DB >> 8676519

C/EBPbeta is a negative regulator of human papillomavirus type 11 in keratinocytes.

H Wang1, K Liu, F Yuan, L Berdichevsky, L B Taichman, K Auborn.   

Abstract

We have evaluated the impact of the CCAAT enhancer-binding protein (C/EBP) transcription factors on human papillomavirus type 11 (HPV11). C/EBPbeta is in nuclei of cultured foreskin keratinocytes and binds its consensus sequence in HPV11 DNA. We have used the novel approach of depleting the availability of C/EBPs in vivo using nuclease-resistant oligomers containing C/EBP DNA binding sites. In cultured foreskin keratinocytes containing replicating HPV11 DNA, levels of both HPV11 transcripts and HPV DNA increase after treatment with oligomers; containing the C/EBPbeta DNA binding motif. These results indicate that C/EBPbeta is a repressor for HPV11 in keratinocytes.

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Year:  1996        PMID： 8676519      PMCID： PMC190429     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  52 in total

1.  Reciprocal regulation of adipogenesis by Myc and C/EBP alpha.

Authors:  S O Freytag; T J Geddes
Journal:  Science       Date:  1992-04-17       Impact factor: 47.728

2.  Heterogeneity in the replicating population of cultured human epidermal keratinocytes.

Authors:  K M Albers; R W Setzer; L B Taichman
Journal:  Differentiation       Date:  1986       Impact factor: 3.880

3.  Multiple interactions between cellular factors and the non-coding region of human papillomavirus type 16.

Authors:  G J Sibbet; M S Campo
Journal:  J Gen Virol       Date:  1990-11       Impact factor: 3.891

4.  Reciprocal expression of NF-IL6 and C/EBP in hepatocytes: possible involvement of NF-IL6 in acute phase protein gene expression.

Authors:  H Isshiki; S Akira; T Sugita; Y Nishio; S Hashimoto; T Pawlowski; S Suematsu; T Kishimoto
Journal:  New Biol       Date:  1991-01

5.  Differentiation-linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes.

Authors:  M H Stoler; S M Wolinsky; A Whitbeck; T R Broker; L T Chow
Journal:  Virology       Date:  1989-09       Impact factor: 3.616

6.  Identification of DNA-protein interactions and enhancer activity at the 5' end of the upstream regulatory region in human papillomavirus type 11.

Authors:  K J Auborn; R L Galli; T P Dilorenzo; B M Steinberg
Journal:  Virology       Date:  1989-05       Impact factor: 3.616

7.  A key DNA-protein interaction determines the function of the 5'URR enhancer in human papillomavirus type 11.

Authors:  K J Auborn; B M Steinberg
Journal:  Virology       Date:  1991-03       Impact factor: 3.616

8.  Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation.

Authors:  M A Bedell; J B Hudson; T R Golub; M E Turyk; M Hosken; G D Wilbanks; L A Laimins
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

Review 9.  CCAAT-enhancer binding protein: a component of a differentiation switch.

Authors:  R M Umek; A D Friedman; S L McKnight
Journal:  Science       Date:  1991-01-18       Impact factor: 47.728

10.  Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells.

Authors:  J G Rheinwald; H Green
Journal:  Cell       Date:  1975-11       Impact factor: 41.582
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  15 in total

1.  Genetic analysis of cis regulatory elements within the 5' region of the human papillomavirus type 31 upstream regulatory region during different stages of the viral life cycle.

Authors:  Ellora Sen; Jennifer L Bromberg-White; Craig Meyers
Journal:  J Virol       Date:  2002-05       Impact factor: 5.103

2.  Differences in C/EBPs in normal tissue and papillomas of the larynx.

Authors:  L Jin; G Y Yang; K Auborn
Journal:  Cell Prolif       Date:  1998 Jun-Aug       Impact factor: 6.831

3.  CCAAT displacement protein, a regulator of differentiation-specific gene expression, binds a negative regulatory element within the 5' end of the human papillomavirus type 6 long control region.

Authors:  S Pattison; D G Skalnik; A Roman
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

4.  Transcription activities of human papillomavirus type 11 E6 promoter-proximal elements in raft and submerged cultures of foreskin keratinocytes.

Authors:  W Zhao; L T Chow; T R Broker
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

5.  Chicken YB-2, a Y-box protein, is a potent activator of Rous sarcoma virus long terminal repeat-driven transcription in avian fibroblasts.

Authors:  S K Swamynathan; A Nambiar; R V Guntaka
Journal:  J Virol       Date:  1997-04       Impact factor: 5.103

6.  Nuclear matrix attachment regions of human papillomavirus type 16 repress or activate the E6 promoter, depending on the physical state of the viral DNA.

Authors:  W Stünkel; Z Huang; S H Tan; M J O'Connor; H U Bernard
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

7.  Induction of the human papillomavirus type 31 late promoter requires differentiation but not DNA amplification.

Authors:  Kathryn M Spink; Laimonis A Laimins
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

8.  C/EBPbeta modulates the early events of keratinocyte differentiation involving growth arrest and keratin 1 and keratin 10 expression.

Authors:  S Zhu; H S Oh; M Shim; E Sterneck; P F Johnson; R C Smart
Journal:  Mol Cell Biol       Date:  1999-10       Impact factor: 4.272

9.  CCAAT displacement protein binds to and negatively regulates human papillomavirus type 6 E6, E7, and E1 promoters.

Authors:  W Ai; E Toussaint; A Roman
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

10.  Identification of an involucrin promoter transcriptional response element with activity restricted to keratinocytes.

Authors:  M A Phillips; Q Qin; R H Rice
Journal:  Biochem J       Date:  2000-05-15       Impact factor: 3.857
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