Literature DB >> 8669190

Influence of smear quality on the rate of detecting significant cervical cytologic abnormalities.

J A Henry1, V Wadehra.   

Abstract

OBJECTIVE: To determine the correlation between cervical smear quality and the rate of detecting significant epithelial abnormalities. STUDY
DESIGN: Smear quality was assessed routinely in a series of 68,328 cervical spatula and spatula/brush combination smears received by our laboratory during 1993. Quality was assessed using a semiquantitative method, evaluating the presence of endocervical cells, metaplastic squamous cells, endocervical mucus and overall squamous cellularity.
RESULTS: Smear quality was graded as unsatisfactory, poor (18,680 smears), fair (9,739 smears) or good (39,909 smears); unsatisfactory smears were eliminated from the analysis. There was a highly significant correlation between smear quality and the rate of detecting significant epithelial abnormalities (chi 2=127.52, df=2, P<.001).
CONCLUSION: Smear quality is an important issue. Many significant abnormalities are potentially missed because of poor smear quality.

Entities:  

Mesh:

Year:  1996        PMID: 8669190     DOI: 10.1159/000333910

Source DB:  PubMed          Journal:  Acta Cytol        ISSN: 0001-5547            Impact factor:   2.319


  4 in total

1.  Effects of transitioning from conventional methods to liquid-based methods on unsatisfactory Papanicolaou tests: results from a multicenter US study.

Authors:  Christopher L Owens; Dan Peterson; Aruna Kamineni; Diana S M Buist; Sheila Weinmann; Tyler R Ross; Andrew E Williams; Azadeh Stark; Kenneth F Adams; Terry S Field
Journal:  Cancer Cytopathol       Date:  2013-05-08       Impact factor: 5.284

2.  Follow-up and clinical significance of unsatisfactory liquid-based Papanicolaou tests.

Authors:  Christopher L Owens; Diana S M Buist; Daniel Peterson; Aruna Kamineni; Sheila Weinmann; Tyler Ross; Andrew E Williams; Azadeh Stark; Kenneth F Adams; Chyke A Doubeni; Terry S Field
Journal:  Cancer Cytopathol       Date:  2014-10-23       Impact factor: 5.284

3.  Outcome of women with inadequate cervical smears followed up for five years.

Authors:  Y L Hock; S Ramaiah; E S Wall; A M Harris; L Marston; J Marshall; K Kendall; A Teale
Journal:  J Clin Pathol       Date:  2003-08       Impact factor: 3.411

4.  Performance of cytology and human papillomavirus testing in relation to the menstrual cycle.

Authors:  M E Sherman; J D Carreon; M Schiffman
Journal:  Br J Cancer       Date:  2006-06-05       Impact factor: 7.640

  4 in total

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