Literature DB >> 866181

Proflavine sensitivity of RNA processing in isolated nuclei.

A Yannarell, M Niemann, D E Schumm, T E Webb.   

Abstract

The intercalating agent proflavine inhibits the processing and subsequent release of preformed messenger RNA and ribosomal RNA from isolated liver nuclei to surrogate cytoplasm. The direct effect of proflavine on these processes, as monitored in a reconstituted cell-free system, supports the theory that base-paired segments (i.e. hairpin loops) in the precursor RNA's are involved as recognition sites in nuclear RNA processing.

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Year:  1977        PMID: 866181      PMCID: PMC342457          DOI: 10.1093/nar/4.3.503

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  17 in total

1.  Presence of sequences hybridisable to dsRNA in cytoplasmic mRNA molecules.

Authors:  H Naora; J M Whitelam
Journal:  Nature       Date:  1975-08-28       Impact factor: 49.962

Review 2.  Eukaryotic messenger RNA.

Authors:  G Brawerman
Journal:  Annu Rev Biochem       Date:  1974       Impact factor: 23.643

3.  Cytoplasmic proteins regulating messenger RNA release from nuclei.

Authors:  D E Schumm; D J McNamara; T E Webb
Journal:  Nat New Biol       Date:  1973-10-17

4.  Processing and release of ribosomal RNA from isolated nuclei: analysis of the ATP-dependence and cytosol-dependence.

Authors:  J Racevskis; T E Webb
Journal:  Eur J Biochem       Date:  1974-11-01

5.  Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing.

Authors:  F Rottman; A J Shatkin; R P Perry
Journal:  Cell       Date:  1974-11       Impact factor: 41.582

6.  Processing of 45 s nucleolar RNA.

Authors:  R A Weinberg; S Penman
Journal:  J Mol Biol       Date:  1970-01-28       Impact factor: 5.469

7.  Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cells.

Authors:  S Penman; C Vesco; M Penman
Journal:  J Mol Biol       Date:  1968-05-28       Impact factor: 5.469

8.  Inhibition of the processing of ribosomal precursor RNA by intercalating agents.

Authors:  A L Snyder; H E Kann; K W Kohn
Journal:  J Mol Biol       Date:  1971-06-14       Impact factor: 5.469

9.  Modified messenger ribonucleic acid release from isolated hepatic nuclei after inhibition of polyadenylate formation.

Authors:  D E Schumm; T E Webb
Journal:  Biochem J       Date:  1974-04       Impact factor: 3.857

10.  Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA.

Authors:  J E Darnell; L Philipson; R Wall; M Adesnik
Journal:  Science       Date:  1971-10-29       Impact factor: 47.728

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  8 in total

1.  Active transport of messenger ribonucleoprotein particles in a reconstituted cell-free system.

Authors:  B T French; D E Schumm; T E Webb
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

2.  An assessment of some methodological criticisms of studies of RNA efflux from isolated nuclei.

Authors:  P S Agutter
Journal:  Biochem J       Date:  1983-09-15       Impact factor: 3.857

3.  Heterogeneous nuclear RNA promotes synthesis of (2',5')oligoadenylate and is cleaved by the (2',5')oligoadenylate-activated endoribonuclease.

Authors:  T W Nilsen; P A Maroney; H D Robertson; C Baglioni
Journal:  Mol Cell Biol       Date:  1982-02       Impact factor: 4.272

4.  Cleavage of pre-mRNA sequences by ribonucleases bound to nuclear RNP particles of rat liver.

Authors:  J Molnár; G Bajszár; I Marczinovits; G Szabó
Journal:  Mol Biol Rep       Date:  1978-10-16       Impact factor: 2.316

5.  Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression.

Authors:  D Eick; G W Bornkamm
Journal:  Nucleic Acids Res       Date:  1986-11-11       Impact factor: 16.971

6.  Studies on transcription termination and splicing of the rRNA precursor in vivo in the presence of proflavine.

Authors:  O F Nielsen; M Carin; O Westergaard
Journal:  Nucleic Acids Res       Date:  1984-01-25       Impact factor: 16.971

7.  Effects of ethidium bromide on the production of ribosomal RNA in cultured mouse cells.

Authors:  M Lange; P May
Journal:  Nucleic Acids Res       Date:  1979-06-25       Impact factor: 16.971

8.  In vitro splicing of the ribosomal RNA precursor in isolated nucleoli from Tetrahymena.

Authors:  M Carin; B F Jensen; K D Jentsch; J C Leer; O F Nielsen; O Westergaard
Journal:  Nucleic Acids Res       Date:  1980-12-11       Impact factor: 16.971

  8 in total

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