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Literature DB >> 8661717

A class of highly polymorphic tetranucleotide repeats for canine genetic mapping.

L V Francisco¹, A A Langston, C S Mellersh, C L Neal, E A Ostrander.

Abstract

We have identified and characterized a new class of polymorphic markers for the canine genome from a simple tetranucleotide repeat sequence, (GAAA)n. Genetic markers derived from this repeat are highly polymorphic compared with other canine microsatellites, yet are stable enough to be useful for following Mendelian inheritance in multigeneration pedigrees. We show further that (GAAA)n repeats are distributed throughout the canine genome and occur with sufficient frequency to be useful in the development of a framework map of the canine genome.

Entities: Chemical Species

Mesh：

Substances：
Genetic Markers

Year: 1996 PMID： 8661717 DOI： 10.1007/s003359900104

Source DB: PubMed Journal: Mamm Genome ISSN： 0938-8990 Impact factor: 2.957

23 in total

A class of highly polymorphic tetranucleotide repeats for canine genetic mapping.

1. Construction of a GT polymorphism map of human 9q.

2. A genetic map of the mouse suitable for typing intraspecific crosses.

Review 3. A comprehensive genetic linkage map of the human genome. NIH/CEPH Collaborative Mapping Group.

4. A second-generation linkage map of the human genome.

5. Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups.

6. Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

7. Mutation of human short tandem repeats.

8. Identification and characterization of dinucleotide repeat (CA)n markers for genetic mapping in dog.

9. Simple sequences are ubiquitous repetitive components of eukaryotic genomes.

10. One hundred and one new simple sequence repeat-based markers for the canine genome.

1. Rescue of a severely bottlenecked wolf (Canis lupus) population by a single immigrant.

2. DNA fingerprinting using microsatellites to solve a parentage testing in the boxer breed.

Review 3. Semper fidelis: what man's best friend can teach us about human biology and disease.

4. Linkage analysis with an interbreed backcross maps Dalmatian hyperuricosuria to CFA03.

5. Conservation genetics of maned wolves in a highly impacted area of the Brazilian Cerrado biome.

6. Towards construction of a canine linkage map: establishment of 16 linkage groups.

7. DNA reviews: hair.

8. Nonhuman DNA.

9. From caveman companion to medical innovator: genomic insights into the origin and evolution of domestic dogs.

10. L-2-hydroxyglutaric aciduria: characterisation of the molecular defect in a spontaneous canine model.