| Literature DB >> 8655570 |
J O Solbiati1, M Ciaccio, R N Farías, R A Salomón.
Abstract
Microcin J25 (MccJ25) is a small peptide antibiotic produced by an Escherichia coli strain isolated from human feces. The genetic determinants for MccJ25 synthesis and immunity have been cloned from the low-copy-number wild-type plasmid pTUC1OO into the compatible vectors pBR322 and pACYC184. Physical and phenotypical analysis of insertion mutations and complementation tests defined three contiguous genes involved in MccJ25 production which span a region of about 2.2 kb. Immunity to the antibiotic is provided by an additional gene adjacent to the production region.Entities:
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Year: 1996 PMID: 8655570 PMCID: PMC178142 DOI: 10.1128/jb.178.12.3661-3663.1996
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490