Literature DB >> 8650824

The changing face of oesophageal cancer treatment in Northern Ireland.

K McManus1, J McGuigan.   

Abstract

In the late 1970's the options for treatment of oesophageal cancer were limited. When cure was thought possible, resection was performed by the Ivor Lewis or oesophagogastrectomy techniques. Mortality was high, local recurrence rates disappointing, and long-term survival poor. For those patients whose tumours could not be resected, palliative intubation required open operation with high morbidity, and gave poor quality of life. In 1994, selective screening is diagnosing cancers early, more extensive resections are possible with lower mortality, and fewer local recurrences. Adjuvant therapy is increasing the operability rates. Gradually the facade of poor prognosis is being etched away, so that more patients are being given better quality of life, and cure is a distinct possibility. Palliation can be achieved endoscopically by dilatation, intubation or laser ablation combined with local external beam radiation. Mortality for palliative procedures is now considerably reduced.

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Mesh:

Year:  1994        PMID: 8650824      PMCID: PMC2448770     

Source DB:  PubMed          Journal:  Ulster Med J        ISSN: 0041-6193


  6 in total

1.  Sutures, staplers, leaks and strictures. A review of anastomoses in oesophageal resection at Royal Victoria Hospital, Belfast 1977-1986.

Authors:  K G McManus; A J Ritchie; J McGuigan; H M Stevenson; J R Gibbons
Journal:  Eur J Cardiothorac Surg       Date:  1990       Impact factor: 4.191

2.  Left-sided subtotal oesophagectomy for carcinoma.

Authors:  H R Matthews; A Steel
Journal:  Br J Surg       Date:  1987-12       Impact factor: 6.939

3.  Palliation and survival in malignant oesophago-respiratory fistula.

Authors:  R M Weaver; H R Matthews
Journal:  Br J Surg       Date:  1980-08       Impact factor: 6.939

Review 4.  Barrett's disease: pathophysiology of metaplasia and adenocarcinoma.

Authors:  M Pera; V F Trastek; P C Pairolero; A Cardesa; M S Allen; C Deschamps
Journal:  Ann Thorac Surg       Date:  1993-11       Impact factor: 4.330

5.  Preoperative chemotherapy, surgical resection, and selective postoperative therapy for squamous cell carcinoma of the esophagus.

Authors:  A D Hilgenberg; R W Carey; E W Wilkins; N C Choi; D J Mathisen; H C Grillo
Journal:  Ann Thorac Surg       Date:  1988-04       Impact factor: 4.330

6.  A controlled trial of an expansile metal stent for palliation of esophageal obstruction due to inoperable cancer.

Authors:  K Knyrim; H J Wagner; N Bethge; M Keymling; N Vakil
Journal:  N Engl J Med       Date:  1993-10-28       Impact factor: 91.245

  6 in total

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