Literature DB >> 8646792

Identification of dioxin-responsive elements (DREs) in the 5' regions of putative dioxin-inducible genes.

Z W Lai1, T Pineau, C Esser.   

Abstract

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an exogenous ligand for the cytosolic aryl hydrocarbon receptor (AhR), a ligand-inducible transcription factor whose exact physiological role remains elusive. TCDD has been shown to modulate the expression of a large array of genes, albeit often indirectly, by demonstration of protein or mRNA upregulation. Here, by computer analysis of available promoter sequences, we identify dioxin-responsive elements in the promoter regions of many putative AhR regulated and therefore dioxin-inducible genes.

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Year:  1996        PMID： 8646792     DOI： 10.1016/0009-2797(96)03691-5

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN： 0009-2797            Impact factor:   5.192


  16 in total

1.  Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences.

Authors:  Y V Sun; D R Boverhof; L D Burgoon; M R Fielden; T R Zacharewski
Journal:  Nucleic Acids Res       Date:  2004-08-24       Impact factor: 16.971

2.  Aryl hydrocarbon receptor-dependent apoptotic cell death induced by the flavonoid chrysin in human colorectal cancer cells.

Authors:  Sean M Ronnekleiv-Kelly; Manabu Nukaya; Carol J Díaz-Díaz; Bryant W Megna; Patrick R Carney; Peter G Geiger; Gregory D Kennedy
Journal:  Cancer Lett       Date:  2015-10-26       Impact factor: 8.679

3.  Gene-chemical interactions in the developing mammalian nervous system: Effects on proliferation, neurogenesis and differentiation.

Authors:  Donald A Fox; Lisa Opanashuk; Aleksander Zharkovsky; Bernie Weiss
Journal:  Neurotoxicology       Date:  2010-04-08       Impact factor: 4.294

4.  Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis.

Authors:  Tultul Nayyar; Kaylon L Bruner-Tran; Dagmara Piestrzeniewicz-Ulanska; Kevin G Osteen
Journal:  Reprod Toxicol       Date:  2006-09-30       Impact factor: 3.143

5.  AhR sensing of bacterial pigments regulates antibacterial defence.

Authors:  Pedro Moura-Alves; Kellen Faé; Erica Houthuys; Anca Dorhoi; Annika Kreuchwig; Jens Furkert; Nicola Barison; Anne Diehl; Antje Munder; Patricia Constant; Tatsiana Skrahina; Ute Guhlich-Bornhof; Marion Klemm; Anne-Britta Koehler; Silke Bandermann; Christian Goosmann; Hans-Joachim Mollenkopf; Robert Hurwitz; Volker Brinkmann; Simon Fillatreau; Mamadou Daffe; Burkhard Tümmler; Michael Kolbe; Hartmut Oschkinat; Gerd Krause; Stefan H E Kaufmann
Journal:  Nature       Date:  2014-08-13       Impact factor: 49.962

6.  TCDD exposure disrupts mammary epithelial cell differentiation and function.

Authors:  Loretta L Collins; Betina J Lew; B Paige Lawrence
Journal:  Reprod Toxicol       Date:  2009-03-13       Impact factor: 3.143

7.  Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Authors:  Nikki B Marshall; William R Vorachek; Linda B Steppan; Dan V Mourich; Nancy I Kerkvliet
Journal:  J Immunol       Date:  2008-08-15       Impact factor: 5.422

8.  Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis.

Authors:  M Jurado; J Sainz; C B Lupiañez; M Martínez-Bueno; J M Sánchez-Maldonado; J Badiola; C Cunha; J Springer; M Lackner; J Segura-Catena; L M Canet; L Alcazar-Fuoli; M A López-Nevot; L Fianchi; J M Aguado; L Pagano; E López-Fernández; M Alarcón-Riquelme; L Potenza; S M Gonçalves; M Luppi; L Moratalla; C Solano; A Sampedro; P González-Sierra; M Cuenca-Estrella; K Lagrou; J A Maertens; C Lass-Flörl; H Einsele; L Vazquez; J Loeffler; R Ríos-Tamayo; A Carvalho
Journal:  Infect Immun       Date:  2020-03-23       Impact factor: 3.441

Review 9.  The aryl hydrocarbon receptor is a modulator of anti-viral immunity.

Authors:  Jennifer L Head; B Paige Lawrence
Journal:  Biochem Pharmacol       Date:  2008-11-05       Impact factor: 5.858

10.  Effect of dioxins on regulation of tyrosine hydroxylase gene expression by aryl hydrocarbon receptor: a neurotoxicology study.

Authors:  Eiichi Akahoshi; Seiko Yoshimura; Saeko Uruno; Mitsuko Ishihara-Sugano
Journal:  Environ Health       Date:  2009-06-06       Impact factor: 5.984
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