Literature DB >> 8641765

Increased numbers of interleukin-12-producing cells in human tuberculosis.

M E Munk1, P Mayer, P Anding, K Feldmann, S H Kaufmann.   

Abstract

Numbers of interleukin-12 (IL-12) producing cells were quantitated in the peripheral blood of healthy donors and tuberculosis patients by the ELISPOT assay. We observed that (i) stimulation with mycobacteria increases numbers of IL-12 producers from healthy donors and (ii) tuberculosis patients have larger numbers of IL-12 producers than healthy donors. Our data emphasize the importance of Il-12 in immunity to tuberculosis.

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Year:  1996        PMID： 8641765      PMCID： PMC173886          DOI： 10.1128/iai.64.3.1078-1080.1996

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  14 in total

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Review 2.  CD4+ T-cell subsets: regulation of differentiation and function.

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