Literature DB >> 8300233

The Mycobacterium bovis 32-kilodalton protein antigen induces human cytotoxic T-cell responses.

M E Munk1, J De Bruyn, H Gras, S H Kaufmann.   

Abstract

The 30-kDa protein (P32) is a mycobacterial secreted antigen which is homologous in Mycobacterium bovis and M. tuberculosis. In vitro, P32 induced T-cell proliferation. M. tuberculosis- or P32-stimulated T-cell lines lysed macrophages pulsed with P32 or M. tuberculosis, respectively. We conclude that P32 stimulates cytotoxic T cells specifically.

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Year:  1994        PMID： 8300233      PMCID： PMC186167          DOI： 10.1128/iai.62.2.726-728.1994

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  24 in total

1.  Cloning and expression of the gene for the cross-reactive alpha antigen of Mycobacterium kansasii.

Authors:  K Matsuo; R Yamaguchi; A Yamazaki; H Tasaka; K Terasaka; T Yamada
Journal:  Infect Immun       Date:  1990-02       Impact factor: 3.441

2.  Nucleotide sequence of the 32 kDa-protein gene (antigen 85 A) of Mycobacterium bovis BCG.

Authors:  L De Wit; A de la Cuvellerie; J Ooms; J Content
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

3.  Characterization of T cell antigens associated with the cell wall protein-peptidoglycan complex of Mycobacterium tuberculosis.

Authors:  P F Barnes; V Mehra; G R Hirschfield; S J Fong; C Abou-Zeid; G A Rook; S W Hunter; P J Brennan; R L Modlin
Journal:  J Immunol       Date:  1989-10-15       Impact factor: 5.422

4.  Cloning, sequence determination, and expression of a 32-kilodalton-protein gene of Mycobacterium tuberculosis.

Authors:  M Borremans; L de Wit; G Volckaert; J Ooms; J de Bruyn; K Huygen; J P van Vooren; M Stelandre; R Verhofstadt; J Content
Journal:  Infect Immun       Date:  1989-10       Impact factor: 3.441

5.  T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein.

Authors:  M E Munk; B Schoel; S Modrow; R W Karr; R A Young; S H Kaufmann
Journal:  J Immunol       Date:  1989-11-01       Impact factor: 5.422

6.  Target cell lysis and IL-2 secretion by gamma/delta T lymphocytes after activation with bacteria.

Authors:  M E Munk; A J Gatrill; S H Kaufmann
Journal:  J Immunol       Date:  1990-10-15       Impact factor: 5.422

7.  T cell response to purified filtrate antigen 85 from Mycobacterium bovis Bacilli Calmette-Guérin (BCG) in leprosy patients.

Authors:  P Launois; K Huygen; J De Bruyn; M N'Diaye; B Diouf; L Sarthouj; J Grimaud; J Millan
Journal:  Clin Exp Immunol       Date:  1991-11       Impact factor: 4.330

8.  Identification and characterization of epitopes shared between the mycobacterial 65-kilodalton heat shock protein and the actively secreted antigen 85 complex: their in situ expression on the cell wall surface of Mycobacterium leprae.

Authors:  A Rambukkana; P K Das; J D Burggraaf; W R Faber; P Teeling; S Krieg; J E Thole; M Harboe
Journal:  Infect Immun       Date:  1992-11       Impact factor: 3.441

9.  Molecular and immunological analysis of a fibronectin-binding protein antigen secreted by Mycobacterium leprae.

Authors:  J E Thole; R Schöningh; A A Janson; T Garbe; Y E Cornelisse; J E Clark-Curtiss; A H Kolk; T H Ottenhoff; R R De Vries; C Abou-Zeid
Journal:  Mol Microbiol       Date:  1992-01       Impact factor: 3.501

10.  Limited clonal heterogeneity of antigen-specific T cells localizing in the pleural space during mycobacterial infection.

Authors:  F Manca; G Rossi; M T Valle; S Lantero; G Li Pira; D Fenoglio; J De Bruin; M Costantini; G Damiani; B Balbi
Journal:  Infect Immun       Date:  1991-02       Impact factor: 3.441
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  10 in total

1.  In vitro levels of interleukin 10 (IL-10) and IL-12 in response to a recombinant 32-kilodalton antigen of Mycobacterium bovis BCG after treatment for tuberculosis.

Authors:  V Hari Sai Priya; B Anuradha; Suman Latha Gaddam; Seyed E Hasnain; K J R Murthy; Vijaya Lakshmi Valluri
Journal:  Clin Vaccine Immunol       Date:  2008-11-05

2.  Comparison of immune responses of mice immunized with five different Mycobacterium bovis BCG vaccine strains.

Authors:  M R Lagranderie; A M Balazuc; E Deriaud; C D Leclerc; M Gheorghiu
Journal:  Infect Immun       Date:  1996-01       Impact factor: 3.441

3.  Vaccination with plasmid DNA encoding mycobacterial antigen 85A stimulates a CD4+ and CD8+ T-cell epitopic repertoire broader than that stimulated by Mycobacterium tuberculosis H37Rv infection.

Authors:  O Denis; A Tanghe; K Palfliet; F Jurion; T P van den Berg; A Vanonckelen; J Ooms; E Saman; J B Ulmer; J Content; K Huygen
Journal:  Infect Immun       Date:  1998-04       Impact factor: 3.441

4.  Fibronectin-binding antigen 85 and the 10-kilodalton GroES-related heat shock protein are the predominant TH-1 response inducers in leprosy contacts.

Authors:  P Launois; M N N'Diaye; J L Cartel; I Mane; A Drowart; J P Van Vooren; J L Sarthou; K Huygen
Journal:  Infect Immun       Date:  1995-01       Impact factor: 3.441

5.  Increased numbers of interleukin-12-producing cells in human tuberculosis.

Authors:  M E Munk; P Mayer; P Anding; K Feldmann; S H Kaufmann
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441

6.  Heterologous expression of the Mycobacterium tuberculosis gene encoding antigen 85A in Corynebacterium glutamicum.

Authors:  K Salim; V Haedens; J Content; G Leblon; K Huygen
Journal:  Appl Environ Microbiol       Date:  1997-11       Impact factor: 4.792

7.  Heterologous priming-boosting immunization of cattle with Mycobacterium tuberculosis 85A induces antigen-specific T-cell responses.

Authors:  Evans L N Taracha; Richard Bishop; Antony J Musoke; Adrian V S Hill; Sarah C Gilbert
Journal:  Infect Immun       Date:  2003-12       Impact factor: 3.441

8.  Identification of murine H2-Dd- and H2-Ab-restricted T-cell epitopes on a novel protective antigen, MPT51, of Mycobacterium tuberculosis.

Authors:  Mina Suzuki; Taiki Aoshi; Toshi Nagata; Yukio Koide
Journal:  Infect Immun       Date:  2004-07       Impact factor: 3.441

9.  Characterization of human Mycobacterium bovis bacille Calmette-Guérin-reactive CD8+ T cells.

Authors:  S M Smith; A S Malin; T Pauline; S E Atkinson; J Content; K Huygen; H M Dockrell
Journal:  Infect Immun       Date:  1999-10       Impact factor: 3.441

10.  Age-related waning of in vitro Interferon-gamma levels against r32kDaBCG in BCG vaccinated children.

Authors:  B Anuradha; C M Santosh; V Hari Sai Priya; G Suman Latha; K J R Murthy; Valluri Vijaya Lakshmi
Journal:  J Immune Based Ther Vaccines       Date:  2007-06-07
  10 in total

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