Literature DB >> 8641753

Platelet-activating-factor-mediated pathogenesis in Lyme disease.

E Isogai1, K Kimura, N Fujii, T Nishikawa, N Ishii, D Postic, G Baranton, H Isogai.   

Abstract

This study describes a role of platelet-activating factor (PAF) as a potential inducer of inflammation in infection with Borrelia burgdorferi. Two approaches were taken. The first involved the use of a PAF antagonist to show the lack of an inflammatory response in skin lesions. The second was to show that the PAF antagonist reduced platelet aggregation when the spirochetes were incubated with polymorphonuclear leukocytes.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8641753      PMCID： PMC173874          DOI： 10.1128/iai.64.3.1026-1029.1996

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  32 in total

1.  Interactions of phagocytes with the Lyme disease spirochete: role of the Fc receptor.

Authors:  J L Benach; H B Fleit; G S Habicht; J L Coleman; E M Bosler; B P Lane
Journal:  J Infect Dis       Date:  1984-10       Impact factor: 5.226

2.  Lyme disease-a tick-borne spirochetosis?

Authors:  W Burgdorfer; A G Barbour; S F Hayes; J L Benach; E Grunwaldt; J P Davis
Journal:  Science       Date:  1982-06-18       Impact factor: 47.728

3.  Lyme disease is a spirochetosis. A review of the disease and evidence for its cause.

Authors:  B W Berger; O J Clemmensen; A B Ackerman
Journal:  Am J Dermatopathol       Date:  1983-04       Impact factor: 1.533

4.  Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin.

Authors:  S M Prescott; G A Zimmerman; T M McIntyre
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

5.  Substrate specificity and partial characterization of the PAF-acylhydrolase in human serum that rapidly inactivates platelet-activating factor.

Authors:  M L Wardlow; C P Cox; K E Meng; D E Greene; R S Farr
Journal:  J Immunol       Date:  1986-05-01       Impact factor: 5.422

6.  Human phagocyte interactions with the Lyme disease spirochete.

Authors:  P K Peterson; C C Clawson; D A Lee; D J Garlich; P G Quie; R C Johnson
Journal:  Infect Immun       Date:  1984-11       Impact factor: 3.441

7.  Diverse Lyme disease spirochetes bind integrin alpha IIb beta 3 on human platelets.

Authors:  J Coburn; S W Barthold; J M Leong
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

8.  Isolation and cultivation of Lyme disease spirochetes.

Authors:  A G Barbour
Journal:  Yale J Biol Med       Date:  1984 Jul-Aug

9.  Infection in rabbits with the Lyme disease spirochete.

Authors:  A N Kornblatt; A C Steere; D G Brownstein
Journal:  Yale J Biol Med       Date:  1984 Jul-Aug

10.  The New Zealand white rabbit: an experimental host for infecting ticks with Lyme disease spirochetes.

Authors:  W Burgdorfer
Journal:  Yale J Biol Med       Date:  1984 Jul-Aug
View more
  3 in total

1.  Species-specific plasmid sequences for PCR identification of the three species of Borrelia burgdorferi sensu lato involved in Lyme disease.

Authors:  M C Misonne; P P Hoet
Journal:  J Clin Microbiol       Date:  1998-01       Impact factor: 5.948

2.  Production of interleukin-8 (IL-8) by cultured endothelial cells in response to Borrelia burgdorferi occurs independently of secreted [corrected] IL-1 and tumor necrosis factor alpha and is required for subsequent transendothelial migration of neutrophils.

Authors:  M J Burns; T J Sellati; E I Teng; M B Furie
Journal:  Infect Immun       Date:  1997-04       Impact factor: 3.441

3.  Host Metabolic Response in Early Lyme Disease.

Authors:  Bryna L Fitzgerald; Claudia R Molins; M Nurul Islam; Barbara Graham; Petronella R Hove; Gary P Wormser; Linden Hu; Laura V Ashton; John T Belisle
Journal:  J Proteome Res       Date:  2020-01-09       Impact factor: 4.466
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.