Literature DB >> 7043737

Lyme disease-a tick-borne spirochetosis?

W Burgdorfer, A G Barbour, S F Hayes, J L Benach, E Grunwaldt, J P Davis.   

Abstract

A treponema-like spirochete was detected in and isolated from adult Ixodes dammini, the incriminated tick vector of Lyme disease. Causally related to the spirochetes may be long-lasting cutaneous lesions that appeared on New Zealand White rabbits 10 to 12 weeks after infected ticks fed on them. Samples of serum from patients with Lyme disease were shown by indirect immunofluorescence to contain antibodies to this agent. It is suggested that the newly discovered spirochete is involved in the etiology of Lyme disease.

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Year:  1982        PMID： 7043737     DOI： 10.1126/science.7043737

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  934 in total

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2.  Identification of 11 pH-regulated genes in Borrelia burgdorferi localizing to linear plasmids.

Authors:  J A Carroll; R M Cordova; C F Garon
Journal:  Infect Immun       Date:  2000-12       Impact factor: 3.441

3.  Evidence for the contribution of point mutations to vlsE variation and for apparent constraints on the net accumulation of sequence changes in vlsE during infection with Lyme disease spirochetes.

Authors:  S Y Sung; J V McDowell; R T Marconi
Journal:  J Bacteriol       Date:  2001-10       Impact factor: 3.490

4.  Telomere resolution in the Lyme disease spirochete.

Authors:  G Chaconas; P E Stewart; K Tilly; J L Bono; P Rosa
Journal:  EMBO J       Date:  2001-06-15       Impact factor: 11.598

5.  PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period.

Authors:  R K Straubinger
Journal:  J Clin Microbiol       Date:  2000-06       Impact factor: 5.948

6.  A second allele of eppA in Borrelia burgdorferi strain B31 is located on the previously undetected circular plasmid cp9-2.

Authors:  J C Miller; J L Bono; K Babb; N El-Hage; S Casjens; B Stevenson
Journal:  J Bacteriol       Date:  2000-11       Impact factor: 3.490

7.  Specific antibodies reactive with the 22-kilodalton major outer surface protein of Borrelia anserina Ni-NL protect chicks from infection.

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Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

8.  A blood meal-induced Ixodes scapularis tick saliva serpin inhibits trypsin and thrombin, and interferes with platelet aggregation and blood clotting.

Authors:  Adriana M G Ibelli; Tae K Kim; Creston C Hill; Lauren A Lewis; Mariam Bakshi; Stephanie Miller; Lindsay Porter; Albert Mulenga
Journal:  Int J Parasitol       Date:  2014-02-28       Impact factor: 3.981

9.  Identification of a new Borrelia species among small mammals in areas of northern Spain where Lyme disease is endemic.

Authors:  Horacio Gil; Marta Barral; Raquel Escudero; Ana L García-Pérez; Pedro Anda
Journal:  Appl Environ Microbiol       Date:  2005-03       Impact factor: 4.792

10.  Disruption of blood meal-responsive serpins prevents Ixodes scapularis from feeding to repletion.

Authors:  Mariam Bakshi; Tae Kwon Kim; Albert Mulenga
Journal:  Ticks Tick Borne Dis       Date:  2018-01-10       Impact factor: 3.744
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