| Literature DB >> 8638112 |
M Matsumoto1, S Mariathasan, M H Nahm, F Baranyay, J J Peschon, D D Chaplin.
Abstract
In mice deficient in either lymphotoxin-alpha (LT-alpha) or the type I tumor necrosis factor (TNF) receptor, but not the type II TNF receptor, germinal centers failed to develop in peripheral lymphoid organs. Germinal center formation was restored in LT-alpha-deficient mice by transplantation of normal bone marrow, indicating that the LT-alpha-expressing cells required to establish this lymphoid structure are derived from bone marrow.Entities:
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Year: 1996 PMID: 8638112 DOI: 10.1126/science.271.5253.1289
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728