| Literature DB >> 8631712 |
D R Koehler1, J Courcelle, P C Hanawalt.
Abstract
We compared the removal of pyrimidine(6-4)pyrimidone photoproducts [(6-4) photoproducts] and cyclobutane pyrimidine dimers (CPDs) from the genome of repair-proficient Escherichia coli, using monoclonal antibodies specific for each type of lesion. We found that (6-4) photoproducts were removed at a higher rate than CPDs in the first 30 min following a moderate UV dose (40 J/m2). The difference in rates was less than that typically reported for cultured mammalian cells, in which the removal of (6-4) photoproducts is far more rapid than that of CPDs.Entities:
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Year: 1996 PMID: 8631712 PMCID: PMC177809 DOI: 10.1128/jb.178.5.1347-1350.1996
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490