Literature DB >> 8629983

Anal pathology in patients with Crohn's disease.

C Platell1, J Mackay, B Collopy, R Fink, P Ryan, R Woods.   

Abstract

BACKGROUND: A distinctive feature of patients suffering from Crohn's disease is a predisposition to develop a variety of anal complications. The aetiology of such conditions is unclear, and the reported incidence of anal involvement in Crohn's disease varies party due to the various criteria used for classification. This study aims to review the management of patients with symptomatic anal pathology associated with Crohn's disease at St Vincent's Hospital, Melbourne.
METHODS: A database of 306 patients with Crohn's disease referred to the department between January 1978 and October 1994 was reviewed to identify those patients with symptomatic anal disease. The anal pathology was recorded and classified. Demographic data and the clinical and surgery history of the patient were recorded.
RESULTS: Of the 306 patients with Crohn's disease, 129 (42.4%) were identified as having symptomatic anal pathology. Patients were likely to present with anal symptoms after they had been diagnosed as having intestinal Crohn's disease (46.1%). The commonest presentations were perianal abscess (29.5%), anal fissure (27.6%), and low anal fistula (26.7%). A minority of patients presented with high/complex anal fistulae (3.8%), or recto-vaginal fistulae (5.2%). Five per cent of patients had Crohn's disease localized to the anal area. The pattern of intestinal disease in the remaining patients was small bowel 21.1%. small bowel and colon 31.9%, and colon 43.0%. A total of 244 local anal and surgical procedures were performed on these patients; the commonest of these were drainage of an abscess (38.5%), examination under anaesthetic (29.1%), and laying open of a low anal fistula (22.5%). Following surgical treatment, the recurrence rate for perianal abscesses was 13%, and for low anal fistulae 6%.
CONCLUSIONS: The majority of patients with Crohn's disease who develop anal pathology have an excellent prognosis. A minority of patients develop complex anal complex anal fistulae and these remain a therapeutic challenge.

Entities:  

Mesh:

Year:  1996        PMID: 8629983     DOI: 10.1111/j.1445-2197.1996.tb00690.x

Source DB:  PubMed          Journal:  Aust N Z J Surg        ISSN: 0004-8682


  8 in total

Review 1.  Multidisciplinary and evidence-based management of fistulizing perianal Crohn's disease.

Authors:  Ricardo Sordo-Mejia; Wolfgang B Gaertner
Journal:  World J Gastrointest Pathophysiol       Date:  2014-08-15

2.  The Use of Temporary Fecal Diversion in Colonic and Perianal Crohn's Disease Does Not Improve Outcomes.

Authors:  Andrea C Bafford; Anastasiya Latushko; Natasha Hansraj; Guruprasad Jambaulikar; Leyla J Ghazi
Journal:  Dig Dis Sci       Date:  2017-05-26       Impact factor: 3.199

3.  The relationship between perianal fistula activity and abdominal adipose tissue in Crohn's disease: an observational study.

Authors:  Ziman Xiong; Ziling Zhou; Luwen Hao; Yuanqiu Li; Xuemei Hu; Daoyu Hu; Yan Luo; Yanchun Wang; Yaqi Shen; Zhen Li
Journal:  Insights Imaging       Date:  2022-09-24

4.  An evaluation of vaginal symptoms in women with Crohn's disease.

Authors:  Deborah B Graham; Jayme R Tishon; Marie L Borum
Journal:  Dig Dis Sci       Date:  2007-09-01       Impact factor: 3.199

5.  Impact of mode of delivery on outcomes in patients with perianal Crohn's disease.

Authors:  Alice G Cheng; Emily C Oxford; Jenny Sauk; Deanna D Nguyen; Vijay Yajnik; Sonia Friedman; Ashwin N Ananthakrishnan
Journal:  Inflamm Bowel Dis       Date:  2014-08       Impact factor: 5.325

6.  Crohn's disease presenting as acute abdomen: Report of two cases.

Authors:  Mahesh Gupta; Subhash Goyal; Rekha Goyal
Journal:  N Am J Med Sci       Date:  2011-04

Review 7.  Medical and surgical management of perianal Crohn's disease.

Authors:  Samuel O Adegbola; Anthea Pisani; Kapil Sahnan; Phil Tozer; Pierre Ellul; Janindra Warusavitarne
Journal:  Ann Gastroenterol       Date:  2018-02-08

8.  Crohn's disease in a developing African mission hospital: a case report.

Authors:  Bamidele Johnson Alegbeleye
Journal:  J Med Case Rep       Date:  2019-03-07
  8 in total

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