Literature DB >> 862248

Human antibody-dependent cell-mediated cytotoxicity against target cells infected with respiratory syncytial virus.

R Scott, M O de Landazuri, P S Gardner, J J Owen.   

Abstract

A chromium release assay was established to study human antibody-dependent cell-mediated cytotoxicity (ADCC) of HEp 2 cells infected with respiratory syncytial (RS) virus. Human peripheral blood lymphocytes in the presence of specific antibody to RS virus caused in vitro lysis of RS virus infected target cells. ADCC was detected in sera of infants with RS virus infections and in specimens of colostrum. The ability of serum or colostrum to mediate the cytotoxic reaction appeared to be related to the level of specific IgG, or IgA antibody to RS virus, as detected by membrane fluorescence. Separation of effector cells by their glass adherence properties showed that the ability to produce cytotoxicity resided in non-adherent effector cells.

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Year:  1977        PMID： 862248      PMCID： PMC1540874     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  24 in total

1.  Respiratory syncytial virus. I. Virus recovery and other observations during 1960 outbreak of bronchiolitis, pneumonia, and minor respiratory diseases in children.

Authors:  R M CHANOCK; H W KIM; A J VARGOSKO; A DELEVA; K M JOHNSON; C CUMMING; R H PARROTT
Journal:  JAMA       Date:  1961-05-27       Impact factor: 56.272

2.  Immunity and immunopathology in virus infections.

Authors:  A C Allison
Journal:  Ann Inst Pasteur (Paris)       Date:  1972-10

3.  Use of the 51 Cr release test to demonstrate patterns of antibody response in humans to herpesvirus types 1 and 2.

Authors:  J W Smith; E Adam; J L Melnick; W E Rawls
Journal:  J Immunol       Date:  1972-09       Impact factor: 5.422

4.  Detection of cell-dependent cytotoxic antibody to cells infected with herpes simplex virus.

Authors:  S L Shore; A J Nahmias; S E Starr; P A Wood; D E McFarlin
Journal:  Nature       Date:  1974-09-27       Impact factor: 49.962

5.  Immunological destruction of herpes simplex virus I infected cells.

Authors:  B Rager-Zisman; B R Bloom
Journal:  Nature       Date:  1974-10-11       Impact factor: 49.962

Review 6.  Cytotoxic effects of lymphoid cells in vitro.

Authors:  P Perlmann; G Holm
Journal:  Adv Immunol       Date:  1969       Impact factor: 3.543

Review 7.  Virus infections and respiratory disease of childhood.

Authors:  P S Gardner
Journal:  Arch Dis Child       Date:  1968-12       Impact factor: 3.791

8.  Detection of antibody to respiratory syncytial virus by membrane fluorescence.

Authors:  R Scott; M O De Landazuri; P S Gardner; J J Owen
Journal:  Clin Exp Immunol       Date:  1976-10       Impact factor: 4.330

9.  Antibody-dependent cellular cytotoxicity (ADCC) against Epstein-Barr virus-determined membrane antigens. I. Reactivity in sera from normal persons and from patients with acute infectious mononucleosis.

Authors:  M Jondal
Journal:  Clin Exp Immunol       Date:  1976-07       Impact factor: 4.330

10.  Prevention of cell-to-cell spread of herpes simplex virus by leukocytes.

Authors:  D L Lodmell; A Niwa; K Hayashi; A L Notkins
Journal:  J Exp Med       Date:  1973-03-01       Impact factor: 14.307
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  17 in total

1.  Human respiratory syncytial virus glycoprotein G expressed from a recombinant vaccinia virus vector protects mice against live-virus challenge.

Authors:  E J Stott; L A Ball; K K Young; J Furze; G W Wertz
Journal:  J Virol       Date:  1986-11       Impact factor: 5.103

Review 2.  Detection, pathogenesis, and therapy of respiratory syncytial virus infections.

Authors:  R C Welliver
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

Review 3.  Respiratory syncytial virus. Brief review.

Authors:  E J Stott; G Taylor
Journal:  Arch Virol       Date:  1985       Impact factor: 2.574

4.  Cefodizime stimulates subpopulations of cells mediating spontaneous or antibody-dependent cytotoxicity in patients with bacterial infections.

Authors:  I O Auer; C Hardörfer; I Zimmermann
Journal:  Infection       Date:  1992       Impact factor: 3.553

5.  Antibodies to T cells in patients with systemic lupus erythematosus can induce antibody-dependent cell-mediated cytotoxicity against human T cells.

Authors:  S Kumagai; A D Steinberg; I Green
Journal:  J Clin Invest       Date:  1981-03       Impact factor: 14.808

6.  Immune status in Crohn's disease. 4. In vitro antibody dependent cell mediated cytotoxicity in peripheral blood.

Authors:  I O Auer; E Ziemer
Journal:  Klin Wochenschr       Date:  1980-08-01

7.  Development of antibody-dependent cell-mediated cytotoxicity in the respiratory tract after natural infection with respiratory syncytial virus.

Authors:  T N Kaul; R C Welliver; P L Ogra
Journal:  Infect Immun       Date:  1982-08       Impact factor: 3.441

8.  Cell-mediated immune response to respiratory syncytial virus infection in owl monkeys.

Authors:  W C Koff; F R Caplan; S Case; S B Halstead
Journal:  Clin Exp Immunol       Date:  1983-08       Impact factor: 4.330

9.  Expression of the fusion protein of human respiratory syncytial virus from recombinant vaccinia virus vectors and protection of vaccinated mice.

Authors:  G W Wertz; E J Stott; K K Young; K Anderson; L A Ball
Journal:  J Virol       Date:  1987-02       Impact factor: 5.103

10.  In vitro cell-dependent lysis of respiratory syncytial virus-infected cells mediated by antibody from local respiratory secretions.

Authors:  M P Cranage; P S Gardner; K McIntosh
Journal:  Clin Exp Immunol       Date:  1981-01       Impact factor: 4.330
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