Literature DB >> 3773052

Human respiratory syncytial virus glycoprotein G expressed from a recombinant vaccinia virus vector protects mice against live-virus challenge.

E J Stott, L A Ball, K K Young, J Furze, G W Wertz.   

Abstract

Recombinant vaccinia virus vectors were constructed which expressed the major surface glycoprotein G of human respiratory syncytial (RS) virus. The biological activity of the G protein expressed from these vectors was assayed. Inoculation of rabbits with live recombinant virus induced high titers of antibody which specifically immunoprecipitated RS virus G protein and was capable of neutralizing RS virus infectivity. Immunization of mice by either the intranasal or the intraperitoneal route with recombinant virus that expressed only the G protein resulted in complete protection of the lower respiratory tract upon subsequent challenge with live RS virus.

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Year:  1986        PMID: 3773052      PMCID: PMC288932     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  33 in total

1.  Respiratory syncytial virus polypeptides: their location in the virion.

Authors:  M Peeples; S Levine
Journal:  Virology       Date:  1979-05       Impact factor: 3.616

2.  Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine.

Authors:  H W Kim; J G Canchola; C D Brandt; G Pyles; R M Chanock; K Jensen; R H Parrott
Journal:  Am J Epidemiol       Date:  1969-04       Impact factor: 4.897

3.  Resistance to human respiratory syncytial virus (RSV) infection induced by immunization of cotton rats with a recombinant vaccinia virus expressing the RSV G glycoprotein.

Authors:  N Elango; G A Prince; B R Murphy; S Venkatesan; R M Chanock; B Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

4.  Respiratory syncytial virus infection in inbred mice.

Authors:  G A Prince; R L Horswood; J Berndt; S C Suffin; R M Chanock
Journal:  Infect Immun       Date:  1979-11       Impact factor: 3.441

5.  A rapid boiling method for the preparation of bacterial plasmids.

Authors:  D S Holmes; M Quigley
Journal:  Anal Biochem       Date:  1981-06       Impact factor: 3.365

6.  Sequencing end-labeled DNA with base-specific chemical cleavages.

Authors:  A M Maxam; W Gilbert
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

Review 7.  The role of viral glycoproteins in adsorption, penetration, and pathogenicity of viruses.

Authors:  P W Choppin; A Scheid
Journal:  Rev Infect Dis       Date:  1980 Jan-Feb

8.  Control of expression of the vaccinia virus thymidine kinase gene.

Authors:  D E Hruby; L A Ball
Journal:  J Virol       Date:  1981-11       Impact factor: 5.103

9.  Distinctive nucleotide sequences adjacent to multiple initiation and termination sites of an early vaccinia virus gene.

Authors:  S Venkatesan; B M Baroudy; B Moss
Journal:  Cell       Date:  1981-09       Impact factor: 41.582

10.  The pathogenesis of respiratory syncytial virus infection in cotton rats.

Authors:  G A Prince; A B Jenson; R L Horswood; E Camargo; R M Chanock
Journal:  Am J Pathol       Date:  1978-12       Impact factor: 4.307

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  39 in total

Review 1.  The respiratory syncitial virus and its role in acute bronchiolitis.

Authors:  M L Everard; A D Milner
Journal:  Eur J Pediatr       Date:  1992-09       Impact factor: 3.183

2.  Increased expression in vivo and in vitro of foreign genes directed by A-type inclusion body hybrid promoters in recombinant vaccinia viruses.

Authors:  S Funahashi; S Itamura; H Iinuma; K Nerome; M Sugimoto; H Shida
Journal:  J Virol       Date:  1991-10       Impact factor: 5.103

3.  Role of individual glycoproteins of human parainfluenza virus type 3 in the induction of a protective immune response.

Authors:  R Ray; B J Glaze; R W Compans
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

Review 4.  Immunity to human and bovine respiratory syncytial virus.

Authors:  T G Kimman; F Westenbrink
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

5.  Replication-competent or attenuated, nonpropagating vesicular stomatitis viruses expressing respiratory syncytial virus (RSV) antigens protect mice against RSV challenge.

Authors:  J S Kahn; A Roberts; C Weibel; L Buonocore; J K Rose
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

6.  Antigenic analysis of the F protein of the bovine respiratory syncytial virus: identification of two distinct antigenic sites involved in fusion inhibition.

Authors:  J P Matheise; K Walravens; A Collard; P Coppe; J J Letesson
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

7.  Human cytotoxic T cells stimulated by antigen on dendritic cells recognize the N, SH, F, M, 22K, and 1b proteins of respiratory syncytial virus.

Authors:  A H Cherrie; K Anderson; G W Wertz; P J Openshaw
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

8.  Recombinant vaccinia viruses carrying the N gene of human respiratory syncytial virus: studies of gene expression in cell culture and immune response in mice.

Authors:  A M King; E J Stott; S J Langer; K K Young; L A Ball; G W Wertz
Journal:  J Virol       Date:  1987-09       Impact factor: 5.103

9.  The membrane-associated and secreted forms of the respiratory syncytial virus attachment glycoprotein G are synthesized from alternative initiation codons.

Authors:  S R Roberts; D Lichtenstein; L A Ball; G W Wertz
Journal:  J Virol       Date:  1994-07       Impact factor: 5.103

10.  Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology.

Authors:  Matthew R Murawski; Lori W McGinnes; Robert W Finberg; Evelyn A Kurt-Jones; Michael J Massare; Gale Smith; Penny M Heaton; Armando E Fraire; Trudy G Morrison
Journal:  J Virol       Date:  2009-11-04       Impact factor: 5.103

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