Literature DB >> 8622413

Hydroxyurea reacts with heme proteins to generate nitric oxide.

R Pacelli, J Taira, J A Cook, D A Wink, M C Krishna.   

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Year:  1996        PMID: 8622413     DOI: 10.1016/s0140-6736(96)91378-1

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


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  14 in total

1.  A role for nitric oxide in hydroxyurea-mediated fetal hemoglobin induction.

Authors:  S Bruce King
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808

2.  The pulmonary physician in critical care * Illustrative case 6: Acute chest syndrome of sickle cell anaemia.

Authors:  V Mak; S C Davies
Journal:  Thorax       Date:  2003-08       Impact factor: 9.139

3.  Total antioxidants status and some hematological values in sickle cell disease patients in steady state.

Authors:  Foluke Fasola; Kayode Adedapo; John Anetor; Modupe Kuti
Journal:  J Natl Med Assoc       Date:  2007-08       Impact factor: 1.798

Review 4.  cGMP modulation therapeutics for sickle cell disease.

Authors:  Nicola Conran; Lidiane Torres
Journal:  Exp Biol Med (Maywood)       Date:  2019-01-28

5.  Nitric oxide-dependent killing of aerobic, anaerobic and persistent Burkholderia pseudomallei.

Authors:  Jessica Jones-Carson; James R Laughlin; Amanda L Stewart; Martin I Voskuil; Andrés Vázquez-Torres
Journal:  Nitric Oxide       Date:  2012-04-10       Impact factor: 4.427

6.  Unlocking the binding and reaction mechanism of hydroxyurea substrates as biological nitric oxide donors.

Authors:  Sai Lakshmana Vankayala; Jacqueline C Hargis; H Lee Woodcock
Journal:  J Chem Inf Model       Date:  2012-05-09       Impact factor: 4.956

7.  Hemolysis-associated priapism in sickle cell disease.

Authors:  Vikki G Nolan; Diego F Wyszynski; Lindsay A Farrer; Martin H Steinberg
Journal:  Blood       Date:  2005-06-28       Impact factor: 22.113

8.  Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase.

Authors:  Vladan P Cokic; Reginald D Smith; Bojana B Beleslin-Cokic; Joyce M Njoroge; Jeffery L Miller; Mark T Gladwin; Alan N Schechter
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808

9.  The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation.

Authors:  Yuval Samuni; Wilmarie Flores-Santana; Murali C Krishna; James B Mitchell; David A Wink
Journal:  Free Radic Biol Med       Date:  2009-05-15       Impact factor: 7.376

10.  Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for gamma-globin gene activation.

Authors:  Tzu-Fang Lou; Manisha Singh; Ashley Mackie; Wei Li; Betty S Pace
Journal:  Exp Biol Med (Maywood)       Date:  2009-08-05
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