Literature DB >> 12531869

A role for nitric oxide in hydroxyurea-mediated fetal hemoglobin induction.

S Bruce King1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12531869      PMCID： PMC151883          DOI： 10.1172/JCI17597

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


× No keyword cloud information.
  17 in total

Review 1.  Mechanism of action of hydroxyurea.

Authors:  J W Yarbro
Journal:  Semin Oncol       Date:  1992-06       Impact factor: 4.929

Review 2.  Mechanism of action of hydroxyurea in the management of sickle cell anemia in adults.

Authors:  S Charache
Journal:  Semin Hematol       Date:  1997-07       Impact factor: 3.851

3.  Hydroxyurea reacts with heme proteins to generate nitric oxide.

Authors:  R Pacelli; J Taira; J A Cook; D A Wink; M C Krishna
Journal:  Lancet       Date:  1996-03-30       Impact factor: 79.321

Review 4.  Pharmacokinetics and pharmacodynamics of hydroxyurea.

Authors:  P R Gwilt; W G Tracewell
Journal:  Clin Pharmacokinet       Date:  1998-05       Impact factor: 6.447

5.  Horseradish peroxidase catalyzed nitric oxide formation from hydroxyurea.

Authors:  Jinming Huang; Erin M Sommers; Daniel B Kim-Shapiro; S Bruce King
Journal:  J Am Chem Soc       Date:  2002-04-03       Impact factor: 15.419

6.  Nitric Oxide Metabolites in Sickle Cell Anemia Patients after Oral Administration of Hydroxyurea; Hemoglobinopathy.

Authors:  Masoud Nahavandi; Melville Q. Wyche; Elliott Perlin; Fatemeh Tavakkoli; Oswaldo Castro
Journal:  Hematology       Date:  2000       Impact factor: 2.269

7.  Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease.

Authors:  Christopher D Reiter; Xunde Wang; Jose E Tanus-Santos; Neil Hogg; Richard O Cannon; Alan N Schechter; Mark T Gladwin
Journal:  Nat Med       Date:  2002-11-11       Impact factor: 53.440

8.  Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase.

Authors:  Vladan P Cokic; Reginald D Smith; Bojana B Beleslin-Cokic; Joyce M Njoroge; Jeffery L Miller; Mark T Gladwin; Alan N Schechter
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808

9.  Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway.

Authors:  T Ikuta; S Ausenda; M D Cappellini
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-06       Impact factor: 11.205

10.  Nitric oxide generation from hydroxyurea via copper-catalyzed peroxidation and implications for pharmacological actions of hydroxyurea.

Authors:  K Sato; T Akaike; T Sawa; Y Miyamoto; M Suga; M Ando; H Maeda
Journal:  Jpn J Cancer Res       Date:  1997-12
View more
  7 in total

Review 1.  Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease.

Authors:  Betty S Pace; Li Liu; Biaoru Li; Levi H Makala
Journal:  Exp Biol Med (Maywood)       Date:  2015-08

2.  Regulation of γ-globin gene expression involves signaling through the p38 MAPK/CREB1 pathway.

Authors:  Valya Ramakrishnan; Betty S Pace
Journal:  Blood Cells Mol Dis       Date:  2011-04-15       Impact factor: 3.039

Review 3.  Changing the Clinical Paradigm of Hydroxyurea Treatment for Sickle Cell Anemia Through Precision Medicine.

Authors:  Min Dong; Patrick T McGann
Journal:  Clin Pharmacol Ther       Date:  2020-10-08       Impact factor: 6.875

4.  Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for gamma-globin gene activation.

Authors:  Tzu-Fang Lou; Manisha Singh; Ashley Mackie; Wei Li; Betty S Pace
Journal:  Exp Biol Med (Maywood)       Date:  2009-08-05

5.  Genetic Modifiers at the Crossroads of Personalised Medicine for Haemoglobinopathies.

Authors:  Coralea Stephanou; Stella Tamana; Anna Minaidou; Panayiota Papasavva; Marina Kleanthous; Petros Kountouris
Journal:  J Clin Med       Date:  2019-11-09       Impact factor: 4.241

6.  Adverse effects of a clinically relevant dose of hydroxyurea used for the treatment of sickle cell disease on male fertility endpoints.

Authors:  Kea M Jones; Mohammad S Niaz; Cynthia M Brooks; Shannon I Roberson; Maria P Aguinaga; Edward R Hills; Valerie Montgomery Rice; Phillip Bourne; Donald Bruce; Anthony E Archibong
Journal:  Int J Environ Res Public Health       Date:  2009-03-16       Impact factor: 3.390

7.  Stroke in a Child with Hemoglobin SC Disease: A Case Report Describing use of Hydroxyurea after Transfusion Therapy.

Authors:  Diana Fridlyand; Caroline Wilder; E Leila Jerome Clay; Bruce Gilbert; Betty S Pace
Journal:  Pediatr Rep       Date:  2017-03-22
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.