Literature DB >> 8617500

Cloning of the human SIX1 gene and its assignment to chromosome 14.

C A Boucher1, N Carey, Y H Edwards, M J Siciliano, K J Johnson.   

Abstract

The recently described murine homeobox genes, Six1 and Six2, which are expressed during development in limb tendons, have also been shown to be expressed in skeletal and smooth muscle, respectively. We have cloned and sequenced a human SIX1 cDNA and shown by Northern blotting that it is expressed in adult skeletal muscle. The cDNA sequence and predicted protein sequence of SIX1 and Six1 are highly homologous, with 98% similarity over the entire predicted amino acid sequence. SIX1 was mapped to human chromosome 14 using a rodent/human somatic cell hybrid panel.

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Year:  1996        PMID: 8617500     DOI: 10.1006/geno.1996.0172

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  15 in total

1.  Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype.

Authors:  Raphaelle Grifone; Christine Laclef; François Spitz; Soledad Lopez; Josiane Demignon; Jacques-Emmanuel Guidotti; Kiyoshi Kawakami; Pin-Xian Xu; Robert Kelly; Basil J Petrof; Dominique Daegelen; Jean-Paul Concordet; Pascal Maire
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272

2.  sine oculis in basal Metazoa.

Authors:  Ilona G Bebenek; Ruth D Gates; Joshua Morris; Volker Hartenstein; David K Jacobs
Journal:  Dev Genes Evol       Date:  2004-06-25       Impact factor: 0.900

3.  Six4, a putative myogenin gene regulator, is not essential for mouse embryonal development.

Authors:  H Ozaki; Y Watanabe; K Takahashi; K Kitamura; A Tanaka; K Urase; T Momoi; K Sudo; J Sakagami; M Asano; Y Iwakura; K Kawakami
Journal:  Mol Cell Biol       Date:  2001-05       Impact factor: 4.272

4.  cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

Authors:  J Khan; M L Bittner; L H Saal; U Teichmann; D O Azorsa; G C Gooden; W J Pavan; J M Trent; P S Meltzer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-09       Impact factor: 11.205

5.  Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site.

Authors:  F Spitz; J Demignon; A Porteu; A Kahn; J P Concordet; D Daegelen; P Maire
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-24       Impact factor: 11.205

Review 6.  The sine oculis homeobox (SIX) family of transcription factors as regulators of development and disease.

Authors:  J P Kumar
Journal:  Cell Mol Life Sci       Date:  2009-02       Impact factor: 9.261

7.  Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis.

Authors:  H L Ford; E N Kabingu; E A Bump; G L Mutter; A B Pardee
Journal:  Proc Natl Acad Sci U S A       Date:  1998-10-13       Impact factor: 11.205

8.  Comparative molecular developmental aspects of the mammalian- and the avian lungs, and the insectan tracheal system by branching morphogenesis: recent advances and future directions.

Authors:  John N Maina
Journal:  Front Zool       Date:  2012-08-07       Impact factor: 3.172

9.  Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells.

Authors:  Zhuowei Li; Jackie Stonehuerner; Robert B Devlin; Yuh-Chin T Huang
Journal:  Environ Health Perspect       Date:  2005-12       Impact factor: 9.031

10.  SIX1 overexpression in diffuse-type and grade III gastric tumors: Features that are associated with poor prognosis.

Authors:  Modjtaba Emadi-Baygi; Parvaneh Nikpour; Elaheh Emadi-Andani
Journal:  Adv Biomed Res       Date:  2015-07-27
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