Literature DB >> 8616750

Manual dissection of adenocarcinoma of the lower third of the rectum specimens for detection of lymph node metastases smaller than 5 mm.

S Andreola1, E Leo, F Belli, R Bufalino, G Tomasic, C Lavarino, M T Baldini, E Meroni.   

Abstract

BACKGROUND: The question of whether manual dissection when searching for metastatic lymph nodes from rectal cancer (less than 5 mm) is a reliable method remains controversial.
METHODS: We examined 50 consecutive cases of primary adenocarcinoma of the rectum treated with a sphincter-sparing total rectum resection, total mesorectum excision, and coloanal anastomosis. We used a manual method for the detection of lymph nodes.
RESULTS: One thousand seven hundred ninety-three lymph nodes were found (mean, 36 per patient). One hundred seventy-four contained metastases. Seventy-nine (45.4%) of the affected lymph nodes were less than 5 mm in greatest dimension. The percentage of metastases to small lymph nodes was similar to the percentage reported by Kotanagi (50%), but lower than the report of Herrera (78%), who used a clearing technique to search for regional lymph nodes.
CONCLUSIONS: A median 17 months follow-up in these patients demonstrated that metastases in small lymph nodes are important in the accurate staging of rectal tumors and that a manual method of searching for small lymph nodes is reliable.

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Mesh:

Year:  1996        PMID: 8616750     DOI: 10.1002/(SICI)1097-0142(19960215)77:4<607::AID-CNCR4>3.0.CO;2-D

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  11 in total

1.  Morphological characteristics of lateral pelvic lymph nodes in rectal carcinoma.

Authors:  Hiroyoshi Matsuoka; Tadahiko Masaki; Masanori Sugiyama; Yutaka Atomi; Yasuo Ohkura; Atsuhiko Sakamoto
Journal:  Langenbecks Arch Surg       Date:  2007-03-23       Impact factor: 3.445

2.  How many lymph nodes to stage colorectal carcinoma?

Authors:  K S Mainprize; H Kulacoglu; J Hewavisinthe; A Savage; N Mortensen; B F Warren
Journal:  J Clin Pathol       Date:  1998-02       Impact factor: 3.411

3.  Surgery has a key role for quality assurance of colorectal cancer screening programs: impact of the third level multidisciplinary team on lymph nodal staging.

Authors:  Francesco Bianco; Silvia De Franciscis; Andrea Belli; Maria Di Lena; Antonio Avallone; Maria Antonia Bianco; Sabato Di Marzo; Letizia Gigli; Gianluca Rotondano; Silvana Russo Spena; Fabiana Tatangelo; Alfonso Tempesta; Giovanni Maria Romano
Journal:  Int J Colorectal Dis       Date:  2015-12-29       Impact factor: 2.571

4.  Diffusion-weighted magnetic resonance imaging for detecting lymph node metastasis of rectal cancer.

Authors:  Yo Mizukami; Shugo Ueda; Akiyoshi Mizumoto; Tetsuro Sasada; Ryosuke Okumura; Shigene Kohno; Arimichi Takabayashi
Journal:  World J Surg       Date:  2011-04       Impact factor: 3.352

5.  Clinical and pathologic factors that predict lymph node yield from surgical specimens in colorectal cancer: a population-based study.

Authors:  Joanne F Chou; David Row; Mithat Gonen; Yi-Hai Liu; Deborah Schrag; Martin R Weiser
Journal:  Cancer       Date:  2010-06-01       Impact factor: 6.860

6.  How many lymph nodes are necessary to stage early and advanced adenocarcinoma of the sigmoid colon and upper rectum?

Authors:  Sebastian Leibl; Oleksiyy Tsybrovskyy; Helmut Denk
Journal:  Virchows Arch       Date:  2003-07-03       Impact factor: 4.064

Review 7.  Evolving treatment strategies for colorectal cancer: a critical review of current therapeutic options.

Authors:  Daniel C Damin; Anderson R Lazzaron
Journal:  World J Gastroenterol       Date:  2014-01-28       Impact factor: 5.742

8.  [Lymph node dissection after primary surgery and neoadjuvant radiochemotherapy of rectal cancer. Interim analysis of a multicenter prospective observational study (OCUM)].

Authors:  M E Kreis; C A Maurer; R Ruppert; H Ptok; J Strassburg; T Junginger; S Merkel; P Hermanek
Journal:  Chirurg       Date:  2015-12       Impact factor: 0.955

9.  The number of lymph nodes is correlated with mesorectal morphometry.

Authors:  N Pirro; C Pignodel; P Cathala; P Fabbro-Peray; G Godlewski; M Prudhomme
Journal:  Surg Radiol Anat       Date:  2008-02-26       Impact factor: 1.246

10.  Endoscopic posterior mesorectal resection as an option to combine local treatment of early stage rectal cancer with partial mesorectal lymphadenectomy.

Authors:  Jörg Köninger; Beat P Müller-Stich; Frank Autschbach; Peter Kienle; Jürgen Weitz; Markus W Büchler; Carsten N Gutt
Journal:  Langenbecks Arch Surg       Date:  2007-07-18       Impact factor: 3.445

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