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Literature DB >> 8614461

Human minisatellite mutation rate after the Chernobyl accident.

Y E Dubrova¹, V N Nesterov, N G Krouchinsky, V A Ostapenko, R Neumann, D L Neil, A J Jeffreys.

Abstract

Germline mutation at human minisatellite loci has been studied among children born in heavily polluted areas of the Mogilev district of Belarus after the Chernobyl accident and in a control population. The frequency of mutation was found to be twice as high in the exposed families as in the control group. Mutation rate in the Mogilev families was correlated with the level of caesium-137 surface contamination, consistent with radiation induction of germline mutation.

Entities: Chemical Species

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Year: 1996 PMID： 8614461 DOI： 10.1038/380683a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

57 in total

1. Lessons from Chernobyl.

Authors: D Williams
Journal: BMJ Date: 2001-09-22

2. A pilot study examining germline minisatellite mutations in the offspring of Danish childhood and adolescent cancer survivors treated with radiotherapy.

Authors: Gwen S Rees; Michael Z Trikic; Jeanette F Winther; E Janet Tawn; Marilyn Stovall; Jørgen H Olsen; Catherine Rechnitzer; Henrik Schrøder; Per Guldberg; John D Boice
Journal: Int J Radiat Biol Date: 2006-03 Impact factor: 2.694

Human minisatellite mutation rate after the Chernobyl accident.

1. Lessons from Chernobyl.

2. A pilot study examining germline minisatellite mutations in the offspring of Danish childhood and adolescent cancer survivors treated with radiotherapy.

3. Molecular aspects of plant adaptation to life in the Chernobyl zone.

4. Chemically induced increases and decreases in the rate of expansion of a CAG*CTG triplet repeat.

5. Cytogenetic effect of low dose gamma-radiation in Hordeum vulgare seedlings: non-linear dose-effect relationship.

Review 6. Comparative genomics and molecular dynamics of DNA repeats in eukaryotes.

7. The adaptive response and protection against heritable mutations and fetal malformation.

8. Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat.

9. Paternal lifestyle as a potential source of germline mutations transmitted to offspring.

10. Elevated minisatellite mutation rate in the post-chernobyl families from ukraine.