Literature DB >> 8612423

Association of pre mortem diagnosis and autopsy findings in pediatric intensive care unit versus emergency department versus ward patients.

B Goldstein1, L Metlay, C Cox, J S Rubenstein.   

Abstract

OBJECTIVE: As part of the overall quality assurance program for the Department of Pediatrics, we determined whether there were differences in the rates of unexpected autopsy findings between pediatric intensive care unit (ICU), emergency department, and ward patients.
DESIGN: Prospective, descriptive study.
SETTING: Tertiary care children's hospital. PATIENTS: Pediatric deaths (n = 212).
INTERVENTIONS: None.
MEASUREMENTS AND MAIN RESULTS: Autopsies were obtained more frequently in emergency department patients (27/29 [93%]) compared with pediatric ICU (88/121 [73%] and ward (42/62 [68%]) patients (p = .03). The medical examiner's cases were more frequently from emergency department patients (22/27 [81%]) compared with pediatric ICU (39/88 [44%]) or ward (11/42 [26%]) patients (p < .001). We found unexpected autopsy findings in 19 (12%) of 157 patients. There were no unexpected findings from the medical examiner's cases. The most common unexpected findings were unidentified infections (n = 7 [three fungal, three viral, and one nonspecific]) and unrecognized cardiac malformations (n = 4). Unexpected findings occurred more frequently in pediatric ICU patients (16/88 [18%]) vs. emergency department (2/27 [7%]) or ward (1/42 [2%]) patients (p = .03). The occurrence rates of major unexpected findings (Class I and II) in pediatric ICU (7/79 [9%]), emergency department (2/27 [7%]), and ward (1/42 [2%]) patients were similar (p = .4). There were two Goldman's Class I unexpected findings in the pediatric ICU and emergency department patients, and one Goldman's Class I unexpected finding in the ward patients.
CONCLUSIONS: Autopsies were performed more frequently in emergency department patients. Class I through IV unexpected findings occurred more frequently in pediatric ICU patients compared with emergency department or ward patients. Autopsy examinations are an especially valuable diagnostic tool for pediatric ICU patients and physicians.

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Mesh:

Year:  1996        PMID: 8612423     DOI: 10.1097/00003246-199604000-00022

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  7 in total

1.  Diagnostic errors in paediatric cardiac intensive care.

Authors:  Priya N Bhat; John M Costello; Ranjit Aiyagari; Paul J Sharek; Claudia A Algaze; Mjaye L Mazwi; Stephen J Roth; Andrew Y Shin
Journal:  Cardiol Young       Date:  2018-02-07       Impact factor: 1.093

2.  Are coroners' necropsies necessary? A prospective study examining whether a "view and grant" system of death certification could be introduced into England and Wales.

Authors:  G N Rutty; R M Duerden; N Carter; J C Clark
Journal:  J Clin Pathol       Date:  2001-04       Impact factor: 3.411

Review 3.  [Clinical autopsies in Switzerland : A status report].

Authors:  A-K Rodewald; P Bode; G Cathomas; H Moch
Journal:  Pathologe       Date:  2017-09       Impact factor: 1.011

4.  Value of postmortem studies in deceased neonatal and pediatric intensive care unit patients.

Authors:  Raphael Widmann; Rosmarie Caduff; Luca Giudici; Qing Zhong; Alexander Vogetseder; Romaine Arlettaz; Bernhard Frey; Holger Moch; Peter K Bode
Journal:  Virchows Arch       Date:  2016-12-14       Impact factor: 4.064

5.  The Value of Autopsy in Neonates in the 21st Century.

Authors:  Joline L H de Sévaux; Peter G J Nikkels; Maarten H Lequin; Floris Groenendaal
Journal:  Neonatology       Date:  2018-10-23       Impact factor: 4.035

6.  PICU Autopsies: Rates, Patient Characteristics, and the Role of the Medical Examiner.

Authors:  Sonali Basu; Richard Holubkov; J Michael Dean; Kathleen L Meert; Robert A Berg; Joseph Carcillo; Christopher J L Newth; Rick E Harrison; Murray M Pollack
Journal:  Pediatr Crit Care Med       Date:  2018-12       Impact factor: 3.624

7.  Body of Evidence: Do Autopsy Findings Impact Medical Malpractice Claim Outcomes?

Authors:  Rajshri M Gartland; Laura C Myers; J Bryan Iorgulescu; Anthony T Nguyen; C Winnie Yu-Moe; Bianca Falcone; Richard Mitchell; Allen Kachalia; Elizabeth Mort
Journal:  J Patient Saf       Date:  2021-12-01       Impact factor: 2.844

  7 in total

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