| Literature DB >> 8611167 |
Abstract
Phosphorylation of c-Jun was stimulated in primary cultured rat liver parenchymal cells by treatment with a coplanar polychlorinated biphenyl congener, 3,3'4,4'5-pentachlorobiphenyl (PenCB), as well as by epidermal growth factor, but was not stimulated by the non-coplanar form. However, the amount of c-Jun mRNA did not increase with PenCB treatment. PenCB may activate a signal-transducing pathway consisting of protein kinases.Entities:
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Year: 1996 PMID: 8611167 PMCID: PMC1216990 DOI: 10.1042/bj3130863
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857