Literature DB >> 8608361

Folate supplementation and methotrexate.

B A Dijkmans1.   

Abstract

This review concentrates on the influence of folate supplementation on the toxicity and efficacy of methotrexate (MTX) in rheumatoid arthritis patients. The design, type of folate supplementation and timing of supplementation vary considerably between the six published controlled studies. Folate supplementation seems to have no effect on the efficacy of MTX but may influence toxicity in a favourable way. Further studies are needed to assess the type of supplementation (folic acid, folinic acid), the predisposing factors for toxicity and cost effectiveness.

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Year:  1995        PMID： 8608361     DOI： 10.1093/rheumatology/34.12.1172

Source DB:  PubMed          Journal:  Br J Rheumatol        ISSN： 0263-7103


  7 in total

Review 1.  Pharmacogenetics in the rheumatic diseases.

Authors:  B N Cronstein
Journal:  Ann Rheum Dis       Date:  2004-11       Impact factor: 19.103

2.  Effect of folic acid on methotrexate induction of sulfotransferases in rats.

Authors:  Sangita Maiti Dutta; Smarajit Maiti; Guangping Chen
Journal:  Drug Metab Lett       Date:  2008-04

3.  Are dietary vitamin D, omega-3 fatty acids and folate associated with treatment results in patients with early rheumatoid arthritis? Data from a Swedish population-based prospective study.

Authors:  Cecilia Lourdudoss; Alicja Wolk; Lena Nise; Lars Alfredsson; Ronald van Vollenhoven
Journal:  BMJ Open       Date:  2017-06-10       Impact factor: 2.692

Review 4.  Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis.

Authors:  Beverley Shea; Michael V Swinden; Elizabeth Tanjong Ghogomu; Zulma Ortiz; Wanruchada Katchamart; Tamara Rader; Claire Bombardier; George A Wells; Peter Tugwell
Journal:  Cochrane Database Syst Rev       Date:  2013-05-31

5.  Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis.

Authors:  M Carmen Montesinos; Avani Desai; Bruce N Cronstein
Journal:  Arthritis Res Ther       Date:  2006-03-06       Impact factor: 5.156

Review 6.  Molecular action of methotrexate in inflammatory diseases.

Authors:  Edwin S L Chan; Bruce N Cronstein
Journal:  Arthritis Res       Date:  2002-03-19

7.  Efficacy of clarithromycin as a protective agent in the methotrexate-induced pulmonary fibrosis model.

Authors:  Serdar Kalemci; Orhan Akpınar; Yelda Dere; Aydın Sarıhan; Arife Zeybek; Özgür Tanriverdi
Journal:  Kardiochir Torakochirurgia Pol       Date:  2018-12-31
  7 in total

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