| Literature DB >> 19356074 |
Sangita Maiti Dutta1, Smarajit Maiti, Guangping Chen.
Abstract
Our earlier investigation showed that MTX is an inducer of rat and human sulfotransferases. Here we report that folic acid treatment inhibited MTX induction of aryl sulfotransferase (AST-IV) in female rat liver and hydroxysteroid sulfotransferase (STa) in male rat liver. This is important for understanding the clinical mechanisms of MTX.Entities:
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Year: 2008 PMID: 19356074 PMCID: PMC3108250 DOI: 10.2174/187231208784040997
Source DB: PubMed Journal: Drug Metab Lett ISSN: 1872-3128