Literature DB >> 8599966

The development of in vivo tracer methods to obtain new information about human disease: a study of the hallucinating brain.

T Jones1, D A Silbersweig, E Stern, L Schnorr, J Seaward, J C Clark, A A Lammertsma, S Grootoonk.   

Abstract

An outline is provided of the development of methodological strategies to address the question of focal cerebral activation during hallucinations in schizophrenic patients. In so doing, the innovation and diligence required to tailor in vivo tracer procedures to specific clinical research issues are highlighted. Attention is drawn to the complexity of methodological advances and the way in which they are based upon close scientific and technical collaboration between clinical scientists, and non-clinical scientists and research support staff.

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Year:  1996        PMID： 8599966     DOI： 10.1007/bf00837633

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  7 in total

1.  Physical performance of a positron tomograph for brain imaging with retractable septa.

Authors:  T J Spinks; T Jones; D L Bailey; D W Townsend; S Grootoonk; P M Bloomfield; M C Gilardi; M E Casey; B Sipe; J Reed
Journal:  Phys Med Biol       Date:  1992-08       Impact factor: 3.609

2.  Noise equivalent count measurements in a neuro-PET scanner with retractable septa.

Authors:  D L Bailey; T Jones; T J Spinks; M C Gilardi; D W Townsend
Journal:  IEEE Trans Med Imaging       Date:  1991       Impact factor: 10.048

3.  Detection of thirty-second cognitive activations in single subjects with positron emission tomography: a new low-dose H2(15)O regional cerebral blood flow three-dimensional imaging technique.

Authors:  D A Silbersweig; E Stern; C D Frith; C Cahill; L Schnorr; S Grootoonk; T Spinks; J Clark; R Frackowiak; T Jones
Journal:  J Cereb Blood Flow Metab       Date:  1993-07       Impact factor: 6.200

4.  Imaging transient, randomly occurring neuropsychological events in single subjects with positron emission tomography: an event-related count rate correlational analysis.

Authors:  D A Silbersweig; E Stern; L Schnorr; C D Frith; J Ashburner; C Cahill; R S Frackowiak; T Jones
Journal:  J Cereb Blood Flow Metab       Date:  1994-09       Impact factor: 6.200

5.  Dopaminergic modulation of impaired cognitive activation in the anterior cingulate cortex in schizophrenia.

Authors:  R J Dolan; P Fletcher; C D Frith; K J Friston; R S Frackowiak; P M Grasby
Journal:  Nature       Date:  1995-11-09       Impact factor: 49.962

6.  A functional neuroanatomy of hallucinations in schizophrenia.

Authors:  D A Silbersweig; E Stern; C Frith; C Cahill; A Holmes; S Grootoonk; J Seaward; P McKenna; S E Chua; L Schnorr
Journal:  Nature       Date:  1995-11-09       Impact factor: 49.962

7.  Dosimetry of intravenously administered oxygen-15 labelled water in man: a model based on experimental human data from 21 subjects.

Authors:  T Smith; C Tong; A A Lammertsma; K R Butler; L Schnorr; J D Watson; S Ramsay; J C Clark; T Jones
Journal:  Eur J Nucl Med       Date:  1994-10
  7 in total

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