Literature DB >> 8591946

In-vitro activities of various antibiotics, alone and in combination with amikacin against Pseudomonas aeruginosa.

A A Gerçeker1, B Gürler.   

Abstract

The in-vitro activities of various antibiotics, either alone or in combination with amikacin were assessed in clinical isolates of Pseudomonas aeruginosa. Clinically relevant synergic interactions were most frequent with piperacillin (92%), ceftazidime (87%) and aztreonam (84%), and less frequent with imipenem (35%). Ciprofloxacin-amikacin showed only an additive effect.

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Year:  1995        PMID： 8591946     DOI： 10.1093/jac/36.4.707

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  6 in total

1.  In Vitro Activity of Imipenem-Relebactam Alone or in Combination with Amikacin or Colistin against Pseudomonas aeruginosa.

Authors:  Tomefa E Asempa; David P Nicolau; Joseph L Kuti
Journal:  Antimicrob Agents Chemother       Date:  2019-08-23       Impact factor: 5.191

2.  Optimization of Synergistic Combination Regimens against Carbapenem- and Aminoglycoside-Resistant Clinical Pseudomonas aeruginosa Isolates via Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling.

Authors:  Rajbharan Yadav; Jürgen B Bulitta; Roger L Nation; Cornelia B Landersdorfer
Journal:  Antimicrob Agents Chemother       Date:  2016-12-27       Impact factor: 5.191

3.  In vitro antimicrobial effects of aztreonam, colistin, and the 3-drug combination of aztreonam, ceftazidime and amikacin on metallo-beta-lactamase-producing Pseudomonas aeruginosa.

Authors:  Shigeharu Oie; Yumi Fukui; Masaya Yamamoto; Yuki Masuda; Akira Kamiya
Journal:  BMC Infect Dis       Date:  2009-08-10       Impact factor: 3.090

4.  Aminoglycoside Concentrations Required for Synergy with Carbapenems against Pseudomonas aeruginosa Determined via Mechanistic Studies and Modeling.

Authors:  Rajbharan Yadav; Jürgen B Bulitta; Elena K Schneider; Beom Soo Shin; Tony Velkov; Roger L Nation; Cornelia B Landersdorfer
Journal:  Antimicrob Agents Chemother       Date:  2017-11-22       Impact factor: 5.191

5.  Use of in vitro critical inhibitory concentration, a novel approach to predict in vivo synergistic bactericidal effect of combined amikacin and piperacillin against Pseudomonas aeruginosa in a systemic rat infection model.

Authors:  Eli Chan; Shufeng Zhou; Sahasranaman Srikumar; Wei Duan
Journal:  Pharm Res       Date:  2006-03-29       Impact factor: 4.200

6.  In-vitro efficacy of synergistic antibiotic combinations in multidrug resistant Pseudomonas aeruginosa strains.

Authors:  Devrim Dundar; Metin Otkun
Journal:  Yonsei Med J       Date:  2009-12-29       Impact factor: 2.759
  6 in total

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