Literature DB >> 858918

Inherited polymorphism of guinea pig factor B and C4: evidence for genetic linkage between the C4 and Bf loci.

D Bitter-Suermann, M Krönke, V Brade, U Hadding.   

Abstract

An inherited structural polymorphism of the guinea pig complement protein C4 and of factor B of the alternative pathway was demonstrated by use of high voltage agarose electrophoresis combined with a subsequent immunofixation technique. No polymorphism of guinea pig C3 could be shown. Three common allelic genes were proven to code for C4-S, C4-S1, and C4-F, respectively. Two common allelic genes are responsible for the Bf-F and Bf-S phenotype expression. A strong linkage disequilibrium between both C4 and Bf was demonstrated.

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Year:  1977        PMID： 858918

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  18 in total

1.  Genetic polymorphism of serum complement components in the chimpanzee.

Authors:  D Raum; H Balner; B H Petersen; C A Alper
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

2.  C4 genes of the chimpanzee, gorilla, and orang-utan: evidence for extensive homogenization.

Authors:  H Kawaguchi; Z Zaleska-Rutczynska; F Figueroa; C O'hUigin; J Klein
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

3.  Studies on murine Ss protein: demonstration that S region encodes structural gene for fourth component of complement.

Authors:  M C Carroll; J D Capra
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

4.  Two HLA-linked loci controlling the fourth component of human complement.

Authors:  G J O'Neill; S Y Yang; B Dupont
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

5.  The C4 system: formal and population genetics.

Authors:  B Olaisen; P Teisberg; R Jonassen; T Gedde-Dahl
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

Review 6.  Molecular genetics of the major histocompatibility linked complement genes.

Authors:  H R Colten
Journal:  Springer Semin Immunopathol       Date:  1983

7.  Statement on the nomenclature of dog C4 allotypes.

Authors:  G Doxiadis; W Schoen; I Doxiadis; H J Deeg; G J O'Neill; H Grosse-Wilde
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

8.  Multiple duplications of complement C4 gene correlate with H-2-controlled testosterone-independent expression of its sex-limited isoform, C4-Slp.

Authors:  M Levi-Strauss; M Tosi; M Steinmetz; J Klein; T Meo
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

9.  BF types and the mode of inheritance of insulin-dependent diabetes mellitus (IDDM).

Authors:  D Raum; Z Awdeh; C A Alper
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

10.  There are two C4 genetic loci and a null allele in the chimpanzee.

Authors:  J Granados; Z L Awdeh; J H Chen; C M Giles; H Balner; E J Yunis; C A Alper
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846
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